IGFL3 Protein (AA 25-140) (DYKDDDDK Tag)
(1 reference)-
- 抗原 See all IGFL3 products
- IGFL3 (IGF-Like Family Member 3 (IGFL3))
- 蛋白类型
- Recombinant
- 产品特性
- AA 25-140
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宿主
- 小鼠
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资源
- HEK-293 Cells
- 标记
- This IGFL3 protein is labelled with DYKDDDDK Tag.
- 应用范围
- SDS-PAGE (SDS)
- 交叉反应
- 小鼠
- 产品特性
- Mouse IGFL (aa 25-140) is fused at the N-terminus to a FLAG®-tag.
- 纯度
- >95 % (SDS-PAGE)
- 内毒素水平
- <0.1EU/μg purified protein (LAL test, Lonza).
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IGF-Like Family Member 3 (IGFL3) (AA 25-125) protein (His tag)
Crystallography grade IGFL3 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, Crys, ELISA, WB
IGF-Like Family Member 3 (IGFL3) (AA 25-140) protein (His tag)Crystallography grade IGFL3 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, Crys, ELISA, WB
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Reconstitute with 100 μL sterile water.
- 浓度
- Lot specific
- 缓冲液
- Lyophilized. Contains PBS.
- 储存条件
- 4 °C,-20 °C
- 储存方法
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Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 6 months after receipt when stored at -20°C. - 有效期
- 6 months
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: "Murine insulin growth factor-like (IGFL) and human IGFL1 proteins are induced in inflammatory skin conditions and bind to a novel tumor necrosis factor receptor family member, IGFLR1." in: The Journal of biological chemistry, Vol. 286, Issue 21, pp. 18969-81, (2011) (PubMed).
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: "Murine insulin growth factor-like (IGFL) and human IGFL1 proteins are induced in inflammatory skin conditions and bind to a novel tumor necrosis factor receptor family member, IGFLR1." in: The Journal of biological chemistry, Vol. 286, Issue 21, pp. 18969-81, (2011) (PubMed).
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- 抗原
- IGFL3 (IGF-Like Family Member 3 (IGFL3))
- 别名
- IGFL (IGFL3 产品)
- 别名
- UNQ483 Protein, Gm580 Protein, Igfl Protein, Rprc483 Protein, Ceacam12 Protein, IGF like family member 3 Protein, IGF-like family member 3 Protein, IGFL3 Protein, Igfl3 Protein
- 背景
- Insulin-growth factor-like gene family is a new family of proteins consisting of four proteins in humans (IGFL1 to 4) and one in mice (mIGFL). mIGFL is expressed in normal skin in mice and further upregulated during inflammation responses in skin or after skin wounding. In human only IGFL1 expression is increased in psoriatic skin samples. mIGFL and human IGFL1 and 3 interact with specificity and high affinity to a novel receptor named IGF-like family receptor 1 (formerly TMEM-149). Analysis of the amino acid sequence of IGFLR1 indicated that this receptor is likely a novel member of the TNF-R family. IGFLR1 is expressed most abundantly on mouse T cells, suggesting that mIGFL and IGFL1 produced in the skin may potentially exert regulatory functions on T cell responses.
- 分子量
- ~12kDa (SDS-PAGE)
- UniProt
- Q6B9Z0
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