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IGF-like family receptor 1 (IGFLR1) (AA 23-154) protein (Fc Tag)

IGFLR1 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % (SDS-PAGE) SDS
产品编号 ABIN1344141
发货至: 中国
  • 抗原 See all IGF-like family receptor 1 (IGFLR1) 蛋白
    IGF-like family receptor 1 (IGFLR1)
    蛋白类型
    Recombinant
    产品特性
    AA 23-154
    宿主
    • 4
    • 3
    • 1
    资源
    • 5
    • 2
    • 1
    HEK-293 Cells
    标记
    Fc Tag
    应用范围
    SDS-PAGE (SDS)
    特异性
    Binds to its ligand IGFL3 (human) in the subnanomolar range (< 1 ng /mL).
    交叉反应
    产品特性
    Human IGFLR1 (aa 23-154) is fused at the C-terminus to the Fc portion of human IgG1.
    纯度
    >95 % (SDS-PAGE)
    内毒素水平
    <0.05EU/μg purified protein (LAL test, Lonza).
    Top Product
    Discover our top product IGFLR1 蛋白
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Reconstitute with 50 μL sterile water.
    浓度
    Lot specific
    缓冲液
    Lyophilized. Contains PBS.
    储存条件
    4 °C,-20 °C
    储存方法
    Short Term Storage: +4°C
    Long Term Storage: -20°C
    Stable for at least 6 months after receipt when stored at -20°C.
    有效期
    6 months
  • 抗原
    IGF-like family receptor 1 (IGFLR1)
    别名
    IGFLR1 (IGFLR1 产品)
    背景
    Insulin-growth factor-like gene family is a new family of proteins consisting of four proteins in humans (IGFL1 to 4) and one in mice (mIGFL). mIGFL is expressed in normal skin in mice and further upregulated during inflammation responses in skin or after skin wounding. In human only IGFL1 expression is increased in psoriatic skin samples. mIGFL and human IGFL1 and 3 interact with specificity and high affinity to a novel receptor named IGF-like family receptor 1 (formerly TMEM-149). Analysis of the amino acid sequence of IGFLR1 indicated that this receptor is likely a novel member of the TNF-R family. IGFLR1 is expressed most abundantly on mouse T cells, suggesting that mIGFL and IGFL1 produced in the skin may potentially exert regulatory functions on T cell responses.
    分子量
    ~50kDa (SDS-PAGE)
    UniProt
    Q9H665
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