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GREM1 Protein (His tag)

GREM1 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 90 % by SDS - PAGE SDS
产品编号 ABIN1098774
发货至: 中国
  • 抗原 See all GREM1 蛋白
    GREM1 (Gremlin 1 (GREM1))
    蛋白类型
    Recombinant
    宿主
    • 14
    • 4
    • 4
    • 3
    • 1
    • 1
    资源
    • 12
    • 4
    • 4
    • 3
    • 2
    • 2
    大肠杆菌(E. Coli)
    标记
    This GREM1 protein is labelled with His tag.
    应用范围
    SDS-PAGE (SDS)
    纯度
    > 90 % by SDS - PAGE
    Top Product
    Discover our top product GREM1 蛋白
  • 说明

    Synonyms: Gremlin-1 isoform 1, CKTSF1B1, DAND2, DRM, GREMLIN, IHG-2, PIG2

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.5 mg/ml (determined by Bradford assay)
    缓冲液
    20 mM Tris-HCl buffer (pH 8.0) containing 0.4 M Urea, 10% glycerol
    储存条件
    4 °C
    储存方法
    Avoid repeated freezing and thawing cycles.
  • 抗原
    GREM1 (Gremlin 1 (GREM1))
    别名
    GREM1 (GREM1 产品)
    别名
    grem1 Protein, MGC136702 Protein, zgc:136702 Protein, GREM1 Protein, drm Protein, pig2 Protein, dand2 Protein, ihg-2 Protein, gremlin Protein, Cktsf1b1 Protein, Drm Protein, Grem Protein, ld Protein, gremlin-1 Protein, CKTSF1B1 Protein, DAND2 Protein, DRM Protein, GREMLIN Protein, IHG-2 Protein, cktsf1b1 Protein, gremlin 1a, DAN family BMP antagonist Protein, gremlin 1, DAN family BMP antagonist Protein, gremlin 1 Protein, gremlin 1, DAN family BMP antagonist L homeolog Protein, grem1a Protein, GREM1 Protein, LOC662541 Protein, grem1 Protein, Grem1 Protein, grem1.L Protein
    背景
    GREM1 is a member of the BMP (bone morphogenic protein) antagonist family. Like BMPs, BMP antagonists contain cystine knots and typically form homo- and heterodimers. The CAN (cerberus and dan) subfamily of BMP antagonists, to which this protein belongs, is characterized by a C-terminal cystine knot with an eight-membered ring. The antagonistic effect of the secreted glycosylated protein is likely due to its direct binding to BMP proteins. As an antagonist of BMP, this protein may play a role in regulating organogenesis, body patterning, and tissue differentiation. In mouse, this protein has been shown to relay the sonic hedgehog (SHH) signal from the polarizing region to the apical ectodermal ridge during limb bud outgrowth. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. Recombinant human GREM1 protein, fused to His-tag at N-terminus, was expressed in E.coli.
    分子量
    20.7 kDa (183aa)
    NCBI登录号
    NP_037504
    途径
    Regulation of Muscle Cell Differentiation, Tube Formation, Maintenance of Protein Location
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