DEDD Protein (His tag)
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- 抗原 See all DEDD 蛋白
- DEDD (Death Effector Domain Containing (DEDD))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- 大肠杆菌(E. Coli)
- 标记
- This DEDD protein is labelled with His tag.
- 应用范围
- SDS-PAGE (SDS)
- 纯度
- > 85 % by SDS - PAGE
- Top Product
- Discover our top product DEDD 蛋白
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- 说明
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Synonyms: Death effector domain-containing protein, CASP8IP1, DEDD1, DEFT, FLDED1, KE05
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.5 mg/ml (determined by Bradford assay)
- 缓冲液
- 20 mM Tris-HCl buffer (pH 8.0) containing 0.4 M Urea, 10% glycerol
- 储存条件
- 4 °C
- 储存方法
- Avoid repeated freezing and thawing cycles.
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- 抗原
- DEDD (Death Effector Domain Containing (DEDD))
- 别名
- DEDD (DEDD 产品)
- 别名
- CASP8IP1 Protein, DEDD1 Protein, DEFT Protein, FLDED1 Protein, Dedpro1 Protein, KE05 Protein, Deft Protein, death effector domain containing Protein, death effector domain-containing Protein, DEDD Protein, Dedd Protein
- 背景
- Death effector domain-containing protein, also known as DEDD, is a cytoplasmic protein. It translocates to the nucleus during CD95-mediated apoptosis, where it localizes to nucleoli-like structures, activates caspase-6 and specifically inhibits RNA polymerase I-dependent transcription. The cell death activity of DEDD relates to its nuclear localization. DEDD is widely expressed in a variety of tissues, with highest levels in the testis. Overexpression of this gene was shown to induce weak apoptosis. Recombinant human DEDD protein, fused to His-tag at N-terminus, was expressed in E.coli.
- 分子量
- 38.9 kDa (338aa)
- NCBI登录号
- NP_127491
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