电话:
400-7060-959
传真:
+86 10 56315212-8813
电子邮件:
orders@antibodies-online.cn

PRKAB2 Protein (His tag)

PRKAB2 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 90 % by SDS - PAGE SDS
产品编号 ABIN1098705
发货至: 中国
  • 抗原 See all PRKAB2 蛋白
    PRKAB2 (Protein Kinase, AMP-Activated, beta 2 Non-Catalytic Subunit (PRKAB2))
    蛋白类型
    Recombinant
    宿主
    • 5
    • 1
    • 1
    资源
    • 2
    • 2
    • 2
    • 1
    大肠杆菌(E. Coli)
    标记
    This PRKAB2 protein is labelled with His tag.
    应用范围
    SDS-PAGE (SDS)
    纯度
    > 90 % by SDS - PAGE
    Top Product
    Discover our top product PRKAB2 蛋白
  • 说明

    Synonyms: 5'-AMP-activated protein kinase subunit beta-2

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1.0 mg/ml (determined by Bradford assay)
    缓冲液
    20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol 2 M Urea
    储存条件
    4 °C
    储存方法
    Avoid repeated freezing and thawing cycles.
  • 抗原
    PRKAB2 (Protein Kinase, AMP-Activated, beta 2 Non-Catalytic Subunit (PRKAB2))
    别名
    PRKAB2 (PRKAB2 产品)
    别名
    prkab2 Protein, MGC64365 Protein, PRKAB2 Protein, DKFZp469M1118 Protein, 5730553K21Rik Protein, AW049591 Protein, BB124140 Protein, protein kinase, AMP-activated, beta 2 non-catalytic subunit L homeolog Protein, protein kinase AMP-activated non-catalytic subunit beta 2 Protein, protein kinase, AMP-activated, beta 2 non-catalytic subunit Protein, prkab2.L Protein, PRKAB2 Protein, prkab2 Protein, Prkab2 Protein
    背景
    PRKAB2 is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. PRKAB2 may be a positive regulator of AMPK activity. It is highly expressed in skeletal muscle and thus may have tissue-specific roles. Recombinant human PRKAB2 protein, fused to His-tag at N-terminus, was expressed in E.coli.
    分子量
    32.8 kDa(296aa)
    NCBI登录号
    NP_005390
    途径
    AMPK Signaling, Warburg Effect
You are here:
客服