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RCAN3 Protein (His tag)

RCAN3 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 90 % by SDS - PAGE SDS
产品编号 ABIN1098701
发货至: 中国
  • 抗原 See all RCAN3 蛋白
    RCAN3 (RCAN Family Member 3 (RCAN3))
    蛋白类型
    Recombinant
    宿主
    • 3
    • 1
    • 1
    资源
    • 2
    • 1
    • 1
    • 1
    大肠杆菌(E. Coli)
    标记
    This RCAN3 protein is labelled with His tag.
    应用范围
    SDS-PAGE (SDS)
    纯度
    > 90 % by SDS - PAGE
  • 说明

    Synonyms: Calcipressin-3, DSCR1L2, hRCN3, MCIP3, RCN3

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.5 mg/ml (determined by Bradford assay)
    缓冲液
    20 mM Tris-HCl buffer (pH 8.0) containing 2 M Urea, 20% glycerol, 0.2 M NaCl
    储存条件
    4 °C
    储存方法
    Avoid repeated freezing and thawing cycles.
  • 抗原
    RCAN3 (RCAN Family Member 3 (RCAN3))
    别名
    RCAN3 (RCAN3 产品)
    别名
    DSCR1L2 Protein, rcn3 Protein, hrcn3 Protein, mcip3 Protein, dscr1l2 Protein, MGC145788 Protein, MCIP3 Protein, RCN3 Protein, hRCN3 Protein, Dscr1l2 Protein, AU041093 Protein, Csp3 Protein, wu:fc68f05 Protein, zgc:113155 Protein, zgc:91820 Protein, RCAN family member 3 Protein, calcipressin-3 Protein, regulator of calcineurin 3 Protein, RCAN3 Protein, Tsp_08182 Protein, rcan3 Protein, Rcan3 Protein
    背景
    Calcipressin-3, also known as RCAN3, is a 241 amino acid protein that potentially is involved in central nervous system development. RCAN3 inhibits calcineurin-dependent transcriptional responses by binding to the catalytic domain of calcineurin A. Overexpression of calcipressin-3 results in inhibition of calcineurin activity towards the nuclear factor of activated T-cells (NFAT) transcription factors and also downregulates NFAT-dependent cytokine gene expression in activated Jurkat T-cells. Highest expression occurs in heart, skeletal muscle kidney, liver and peripheral blood leukocytes. Recombinant human RCAN3 protein, fused to His-tag at N-terminus, was expressed in E.coli.
    分子量
    23.5 kDa (209aa)
    NCBI登录号
    NP_038469
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