IL12B Protein (AA 23-328) (His tag)
-
- 抗原 See all IL12B 蛋白
- IL12B (Interleukin 12 beta (IL12B))
- 蛋白类型
- Recombinant
- 产品特性
- AA 23-328
-
宿主
- 人
-
资源
- Baculovirus infected Insect Cells
- 标记
- This IL12B protein is labelled with His tag.
- 应用范围
- SDS-PAGE (SDS)
- 序列
-
IWELKKD VYVVELDWYP DAPGEMVVLT CDTPEEDGIT WTLDQSSEVL GSGKTLTIQV KEFGDAGQYT CHKGGEVLSH SLLLLHKKED GIWSTDILKD QKEPKNKTFL RCEAKNYSGR FTCWWLTTIS TDLTFSVKSS RGSSDPQGVT CGAATLSAER VRGDNKEYEY SVECQEDSAC PAAEESLPIE VMVDAVHKLK YENYTSSFFI RDIIKPDPPK NLQLKPLKNS RQVEVSWEYP DTWSTPHSYF SLTFCVQVQG KSKREKKDRV FTDKTSATVI CRKNASISVR AQDRYYSSSW SEWASVPCS - 纯化方法
- purified by using conventional chromatography.
- 纯度
- > 90% by SDS-PAGE
- 内毒素水平
- < 1 EU per 1ug of protein (determined by LAL method)
- Top Product
- Discover our top product IL12B 蛋白
-
Interleukin 12 beta (IL12B) (AA 23-328) protein (His tag)
IL12B 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
Interleukin 12 beta (IL12B) (AA 23-328) protein (His tag)IL12B 宿主: Cynomolgus 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Interleukin 12 beta (IL12B) protein (His tag)IL12B 宿主: 小鼠 宿主: 人细胞 Recombinant > 95 % as determined by SDS-PAGE
Interleukin 12 beta (IL12B) (AA 229-328) protein (GST tag)IL12B 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Interleukin 12 beta (IL12B) (AA 23-328), (full length) protein (GST tag)IL12B 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant 90 % ELISA
Interleukin 12 beta (IL12B) (AA 23-327), (full length) protein (His tag)IL12B 宿主: 绵羊 宿主: 酵母菌 Recombinant > 90 % ELISA
-
- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- 0.25 mg/mL
- 缓冲液
- 20 mM Tris-HCl buffer (pH 8.0) containing 2 mM DTT, 20% glycerol, 100 mM NaCl, 0.1 MM PMSF
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freezing and thawing cycles.
-
- 抗原
- IL12B (Interleukin 12 beta (IL12B))
- 别名
- IL-12 p40 (IL12B 产品)
- 背景
- IL12P40 (interleukin 12 subunit beta), also known as natural killer cell stimulatory factor 2, or cytotoxic lymphocyte maturation factor 2, p40, belongs to the type I cytokine receptor family. This protein is a cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. Interleukin 12 is a disulfide-linked heterodimer composed of the 40 kD cytokine receptor like subunit encoded by this gene, and a 35 kD subunit encoded by IL12A. This cytokine is expressed by activated macrophages that serve as an essential inducer of Th1 cells development. Recombinant human IL12P40 protein, fused to His-tag at C-terminus, was expressed in Hi-5 cell using baculovirus expression system and purified by using conventional chromatography.
- 分子量
- 35.8 kDa (315aa)
- NCBI登录号
- NP_002178
- 途径
- JAK/STAT Signaling, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation
-
