Asialoglycoprotein Receptor 2 Protein (ASGR2) (His tag)
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- 抗原 See all Asialoglycoprotein Receptor 2 (ASGR2) 蛋白
- Asialoglycoprotein Receptor 2 (ASGR2)
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- 大肠杆菌(E. Coli)
- 标记
- This Asialoglycoprotein Receptor 2 protein is labelled with His tag.
- 应用范围
- SDS-PAGE (SDS)
- 纯化方法
- purified by chromatography
- 纯度
- > 90 % by SDS - PAGE
- Top Product
- Discover our top product ASGR2 蛋白
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- 说明
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Synonyms: Asialoglycoprotein receptor 2, ASGP-R2, ASGPR2, CLEC4H2, HBXBP, HL-2
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.5 mg/ml (determined by Bradford assay)
- 缓冲液
- 20 mM Tris-HCl buffer (pH 8.0) containing 0.2 M NaCl, 30% glycerol, 1 MM DTT
- 储存条件
- 4 °C
- 储存方法
- Avoid repeated freezing and thawing cycles.
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- 抗原
- Asialoglycoprotein Receptor 2 (ASGR2)
- 别名
- ASGR2 (ASGR2 产品)
- 别名
- ASGR2 Protein, asgr2 Protein, MGC137129 Protein, ASGP-R2 Protein, ASGPR2 Protein, CLEC4H2 Protein, HBXBP Protein, HL-2 Protein, Asgr Protein, Asgr-2 Protein, asialoglycoprotein receptor 2 Protein, C-type lectin domain family 10 member A Protein, ASGR2 Protein, clec10a Protein, Asgr2 Protein, LOC100347178 Protein
- 背景
- ASGR2 is a subunit of the asialoglycoprotein receptor. This receptor is a transmembrane protein that plays a critical role in serum glycoprotein homeostasis by mediating the endocytosis and lysosomal degradation of glycoproteins with exposed terminal galactose or N-acetylgalactosamine residues. It may facilitate hepatic infection by multiple viruses including hepatitis B, and is also a target for liver-specific drug delivery. ASGR2 is a hetero-oligomeric protein composed of major and minor subunits, which are encoded by different genes. ASGR2 is the less abundant minor subunit. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. Recombinant human ASGR2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
- 分子量
- 28.9 kDa (255aa) confirmed by MALDI-TOF
- NCBI登录号
- NP_001172
- 途径
- Thyroid Hormone Synthesis
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