TSC22D3 Protein (His tag)
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- 抗原 See all TSC22D3 蛋白
- TSC22D3 (TSC22 Domain Family, Member 3 (TSC22D3))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- 大肠杆菌(E. Coli)
- 标记
- This TSC22D3 protein is labelled with His tag.
- 应用范围
- SDS-PAGE (SDS)
- 纯化方法
- purified by chromatography
- 纯度
- > 85 % by SDS - PAGE
- Top Product
- Discover our top product TSC22D3 蛋白
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- 说明
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Synonyms: TSC22 domain family protein 3, DIP, DSIPI, GILZ, hDIP, TSC-22R
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/ml (determined by Bradford assay)
- 缓冲液
- 20 mM Tris-HCl buffer (pH 8.0) containing 0.15 M NaCl, 10% glycerol, 1 MM DTT
- 储存条件
- 4 °C
- 储存方法
- Avoid repeated freezing and thawing cycles.
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- 抗原
- TSC22D3 (TSC22 Domain Family, Member 3 (TSC22D3))
- 别名
- TSC22D3 (TSC22D3 产品)
- 别名
- dsipi Protein, MGC53285 Protein, zgc:65831 Protein, zgc:77028 Protein, TSC22D3 Protein, GILZ Protein, gilz Protein, tsc-22r Protein, DIP Protein, DSIPI Protein, TSC-22R Protein, hDIP Protein, Dsip1 Protein, Gilz Protein, Tilz3 Protein, Dsipi Protein, DSIP Protein, TSC22 domain family member 3 L homeolog Protein, TSC22 domain family, member 3 Protein, TSC22 domain family member 3 Protein, tsc22d3.L Protein, tsc22d3 Protein, TSC22D3 Protein, Tsc22d3 Protein
- 背景
- TSC22 domain family protein 3, also known as TSC22D3, protects T-cells from IL2 deprivation-induced apoptosis through the inhibition of FOXO3A transcriptional activity that leads to the down-regulation of the pro-apoptotic factor BCL2L11. In macrophages, TSC22D3 plays a role in the anti-inflammatory and immunosuppressive effects of glucocorticoids and IL10. In T-cells, TSC22D3 inhibits anti-CD3-induced NFKB1 nuclear translocation. In vitro, suppresses AP1 and NFKB1 DNA-binding activities. Recombinant human TSC22D3 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
- 分子量
- 17.2 kDa (157aa) confirmed by MALDI-TOF
- NCBI登录号
- NP_004080
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