ARFIP2 Protein (His tag)
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- 抗原 See all ARFIP2 蛋白
- ARFIP2 (ADP-Ribosylation Factor Interacting Protein 2 (ARFIP2))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- 大肠杆菌(E. Coli)
- 标记
- This ARFIP2 protein is labelled with His tag.
- 应用范围
- SDS-PAGE (SDS)
- 纯化方法
- purified by chromatography
- 纯度
- > 90 % by SDS - PAGE
- Top Product
- Discover our top product ARFIP2 蛋白
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- 说明
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Synonyms: Arfaptin 2, POR1
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.25 mg/ml (determined by Bradford assay)
- 缓冲液
- 20 mM Tris-HCl buffer (pH 8.0) containing 0.2 M NaCl, 40% glycerol,1 MM DTT
- 储存条件
- 4 °C
- 储存方法
- Avoid repeated freezing and thawing cycles.
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- 抗原
- ARFIP2 (ADP-Ribosylation Factor Interacting Protein 2 (ARFIP2))
- 别名
- ARFIP2 (ARFIP2 产品)
- 别名
- POR1 Protein, 2310002N04Rik Protein, POR Protein, Por1 Protein, ARFIP2 Protein, im:7136059 Protein, zgc:112066 Protein, ADP ribosylation factor interacting protein 2 Protein, ADP-ribosylation factor interacting protein 2 Protein, ADP-ribosylation factor interacting protein 2b Protein, ARFIP2 Protein, Arfip2 Protein, arfip2b Protein
- 背景
- Arfaptin 2, also known as ARFIP2, is a Rac1 binding protein necessary for Rac-mediated actin polymerization and the subsequent formation of membrane ruffles and lamellipodia. ARFIP2 has also been shown to interact with the ADP ribosylation factor ARF6, a GTPase that associates with the plasma membrane and intracellular endosome vesicles, in a GTP dependent manner. Arfaptin 2 also regulates the aggregation of mutant Huntingtin protein by possibly impairing proteasome function. Expression of ARFIP2 was shown to be increased at sites of neurodegeneration. Recombinant human ARFIP2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
- 分子量
- 40.2 kDa (364aa), confirmed by MALDI-TOF
- NCBI登录号
- NP_036534
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