CKMT1A Protein (His tag)
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- 抗原 See all CKMT1A 蛋白
- CKMT1A (Creatine Kinase, Mitochondrial 1A (CKMT1A))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- 大肠杆菌(E. Coli)
- 标记
- This CKMT1A protein is labelled with His tag.
- 应用范围
- SDS-PAGE (SDS)
- 纯化方法
- purified by chromatography
- 纯度
- > 95 % by SDS - PAGE
- Top Product
- Discover our top product CKMT1A 蛋白
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- 说明
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Synonyms: Creatine kinase U-type, mitochondrial, CKMT1, CKMT1B, UMTCK
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/ml (determined by Bradford assay)
- 缓冲液
- 20 mM Tris-HCl buffer (pH 8.0) containing 0.15 M NaCl, 10% glycerol
- 储存条件
- 4 °C
- 储存方法
- Avoid repeated freezing and thawing cycles.
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- 抗原
- CKMT1A (Creatine Kinase, Mitochondrial 1A (CKMT1A))
- 别名
- CKMT1A (CKMT1A 产品)
- 别名
- CKMT1 Protein, Mt-CK Protein, ScCKmit Protein, UbCKmit Protein, mi-CK Protein, Ckmt1 Protein, CKMT1B Protein, Mia-CK Protein, U-MtCK Protein, creatine kinase, mitochondrial 1A Protein, creatine kinase U-type, mitochondrial-like Protein, creatine kinase, mitochondrial 1, ubiquitous Protein, creatine kinase U-type, mitochondrial Protein, CKMT1A Protein, LOC100228000 Protein, Ckmt1 Protein, LOC100725326 Protein
- 背景
- Mitochondrial creatine (MtCK) kinase is responsible for the transfer of high energy phosphate from mitochondria to the cytosolic carrier, creatine. It belongs to the creatine kinase isoenzyme family. It exists as two isoenzymes, sarcomeric MtCK and ubiquitous MtCK, encoded by separate genes. Mitochondrial creatine kinase occurs in two different oligomeric forms: dimers and octamers, in contrast to the exclusively dimeric cytosolic creatine kinase isoenzymes. Many malignant cancers with poor prognosis have shown overexpression of ubiquitous mitochondrial creatine kinase, this may be related to high energy turnover and failure to eliminate cancer cells via apoptosis. Recombinant human CKMT1A protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
- 分子量
- 45 kDa (403aa) confirmed by MALDI-TOF
- NCBI登录号
- NP_001015001
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