NMRAL1 Protein (His tag)
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- 抗原 See all NMRAL1 蛋白
- NMRAL1 (NmrA-Like Family Domain Containing 1 (NMRAL1))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 标记
- This NMRAL1 protein is labelled with His tag.
- 应用范围
- SDS-PAGE (SDS)
- 纯化方法
- purified by chromatography
- 纯度
- > 95 % by SDS - PAGE
- Top Product
- Discover our top product NMRAL1 蛋白
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NmrA-Like Family Domain Containing 1 (NMRAL1) (AA 1-299) protein (His tag)
NMRAL1 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE ELISA, WB
NmrA-Like Family Domain Containing 1 (NMRAL1) (AA 1-299) protein (GST tag)NMRAL1 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
NmrA-Like Family Domain Containing 1 (NMRAL1) protein (Myc-DYKDDDDK Tag)NMRAL1 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- 说明
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Synonyms: NmrA-like family domain containing 1, HSCARG, SDR48A1
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.5 mg/ml (determined by Bradford assay)
- 缓冲液
- 20 mM Tris-HCl buffer (pH 8.0) containing 20% glycerol 0.15 M NaCl
- 储存条件
- 4 °C
- 储存方法
- Avoid repeated freezing and thawing cycles.
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- 抗原
- NMRAL1 (NmrA-Like Family Domain Containing 1 (NMRAL1))
- 别名
- NMRAL1 (NMRAL1 产品)
- 别名
- HSCARG Protein, SDR48A1 Protein, 1110025F24Rik Protein, AI256624 Protein, RGD1311451 Protein, NmrA like redox sensor 1 Protein, NmrA-like family domain containing 1 Protein, NMRAL1 Protein, Nmral1 Protein
- 背景
- NMRAL1 is a redox sensor protein that undergoes restructuring and subcellular redistribution in response to changes in intracellular NADPH/NADP+ levels. At low NADPH concentrations the protein is found mainly as a monomer, and binds argininosuccinate synthase (ASS1), the enzyme involved in nitric oxide synthesis. Association with ASS1 impairs its activity and reduces the production of nitric oxide, which subsecuently prevents apoptosis. Under normal NADPH concentrations, the protein is found as a dimer and hides the binding site for ASS1. Recombinant human NMRAL1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
- 分子量
- 35.9kDa(323aa) confirmed by MALDI-TOF
- NCBI登录号
- NP_065728
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