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MMACHC Protein (His tag)

MMACHC 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 90 % by SDS - PAGE SDS
产品编号 ABIN1098298
发货至: 中国
  • 抗原 See all MMACHC 蛋白
    MMACHC (Methylmalonic Aciduria (Cobalamin Deficiency) CblC Type, with Homocystinuria (MMACHC))
    蛋白类型
    Recombinant
    宿主
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    资源
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    大肠杆菌(E. Coli)
    标记
    This MMACHC protein is labelled with His tag.
    应用范围
    SDS-PAGE (SDS)
    纯化方法
    purified by chromatography
    纯度
    > 90 % by SDS - PAGE
    Top Product
    Discover our top product MMACHC 蛋白
  • 说明

    Synonyms: Methylmalonic aciduria and homocystinuria type C protein, RP11-291L19.3, cblC

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.5 mg/ml (determined by Bradford assay)
    缓冲液
    20 mM Tris-HCl buffer (pH 8.0) containing 0.15 M NaCl, 10% glycerol, 1 MM DTT
    储存条件
    4 °C
    储存方法
    Avoid repeated freezing and thawing cycles.
  • 抗原
    MMACHC (Methylmalonic Aciduria (Cobalamin Deficiency) CblC Type, with Homocystinuria (MMACHC))
    别名
    MMACHC (MMACHC 产品)
    别名
    cblC Protein, RP11-291L19.3 Protein, RGD1310806 Protein, 1810037K07Rik Protein, methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria Protein, methylmalonic aciduria cblC type, with homocystinuria Protein, MMACHC Protein, Mmachc Protein
    背景
    The exact function of MMACHC is not known, however, its C-terminal region shows similarity to TonB, a bacterial protein involved in energy transduction for cobalamin (vitamin B12) uptake. Hence, it is postulated that this protein may have a role in the binding and intracellular trafficking of cobalamin. Mutations in this protein are associated with methylmalonic aciduria and homocystinuria type cblC. Recombinant human MMACHC protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
    分子量
    34 kDa (306aa), confirmed by MALDI-TOF
    NCBI登录号
    NP_056321
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