PQBP1 Protein (His tag)
-
- 抗原 See all PQBP1 蛋白
- PQBP1 (Polyglutamine Binding Protein 1 (PQBP1))
- 蛋白类型
- Recombinant
-
宿主
- 人
-
资源
- 大肠杆菌(E. Coli)
- 标记
- This PQBP1 protein is labelled with His tag.
- 应用范围
- SDS-PAGE (SDS)
- 纯化方法
- purified by chromatography
- 纯度
- > 95 % by SDS - PAGE
- Top Product
- Discover our top product PQBP1 蛋白
-
-
- 说明
-
Synonyms: Polyglutamine binding protein 1, MRX55, MRXS3, MRXS8, NPW38, RENS1, SHS
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- 0.5 mg/ml (determined by Bradford assay)
- 缓冲液
- 20 mM Tris-HCl buffer (pH 8.0) containing 0.1 M NaCl, 20% glycerol, 1 MM DTT
- 储存条件
- 4 °C
- 储存方法
- Avoid repeated freezing and thawing cycles.
-
- 抗原
- PQBP1 (Polyglutamine Binding Protein 1 (PQBP1))
- 别名
- PQBP1 (PQBP1 产品)
- 别名
- PQBP1 Protein, MRX55 Protein, MRXS3 Protein, MRXS8 Protein, NPW38 Protein, RENS1 Protein, SHS Protein, PQBP-1 Protein, Sfc2 Protein, npw38 Protein, polyglutamine binding protein 1 Protein, PQBP1 Protein, Pqbp1 Protein
- 背景
- Polyglutamine binding protein 1, also known as PQBP1, is a transcription repressor that associates with polyglutamine tract-containing transcription regulators and causative genes for neurodegenerative disorders. PQBP-1 localizes to the nucleus and is present in neurons throughout the brain, with abundant levels in hippocampus, cerebellar cortex and olfactory bulb. PQBP-1 contains a WWP/WW domain that binds proline-rich motifs and a C2 domain that can influence Ca2+-dependent phospholipid signaling. Recombinant human PQBP1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
- 分子量
- 33 kDa (289aa), confirmed by MALDI-TOF
- NCBI登录号
- NP_005701
- 途径
- Ribonucleoprotein Complex Subunit Organization
-