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TCEA1 Protein (His tag)

TCEA1 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 90 % by SDS - PAGE SDS
产品编号 ABIN1098278
发货至: 中国
  • 抗原 See all TCEA1 蛋白
    TCEA1 (Transcription Elongation Factor A Protein 1 (TCEA1))
    蛋白类型
    Recombinant
    宿主
    • 5
    • 1
    • 1
    资源
    • 2
    • 2
    • 2
    • 1
    大肠杆菌(E. Coli)
    标记
    This TCEA1 protein is labelled with His tag.
    应用范围
    SDS-PAGE (SDS)
    纯化方法
    purified by chromatography
    纯度
    > 90 % by SDS - PAGE
    Top Product
    Discover our top product TCEA1 蛋白
  • 说明

    Synonyms: Transcription elongation factor A protein 1, GTF2S, SII, TCEA, TF2S, TFIIS

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/ml (determined by Bradford assay)
    缓冲液
    20 mM Tris-HCl buffer, pH7.5, 20% glycerol, 1 MM DTT, 50 mM NaCl
    储存条件
    4 °C
    储存方法
    Avoid repeated freezing and thawing cycles.
  • 抗原
    TCEA1 (Transcription Elongation Factor A Protein 1 (TCEA1))
    别名
    TCEA1 (TCEA1 产品)
    别名
    gtf2s Protein, sii Protein, tcea Protein, tf2s Protein, TCEA1 Protein, S-II Protein, GTF2S Protein, SII Protein, TCEA Protein, TF2S Protein, TFIIS Protein, fj48e12 Protein, wu:fj48e12 Protein, zgc:63975 Protein, transcription elongation factor A (SII), 1 Protein, transcription elongation factor A1 Protein, transcription elongation factor A (SII) 1 Protein, transcription elongation factor A (SII), 1 L homeolog Protein, tcea1 Protein, TCEA1 Protein, Tcea1 Protein, tcea1.L Protein
    背景
    TCEA1 (Transcription elongation factor A protein 1) belongs to the TFS-II family. TCEA1 binds to Pol II and functions to cleave the nascent transcript, thereby unlocking the complex and allowing transcription to continue. Localized to the nucleus, TCEA1 contains three independently-folding domains, all of which are necessary for proper binding to Pol II. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by S-II allows the resumption of elongation from the new 3'-terminus. Recombinant human TCEA1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
    分子量
    36.5kDa (325aa), confirmed by MALDI-TOF
    NCBI登录号
    NP_006747
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