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OTC Protein (His tag)

OTC 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 90 % by SDS - PAGE SDS
产品编号 ABIN7279762
发货至: 中国
  • 抗原 See all OTC 蛋白
    OTC (Ornithine Carbamoyltransferase (OTC))
    蛋白类型
    Recombinant
    宿主
    • 5
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    资源
    • 11
    • 7
    • 1
    • 1
    大肠杆菌(E. Coli)
    标记
    This OTC protein is labelled with His tag.
    应用范围
    SDS-PAGE (SDS)
    纯化方法
    purified by chromatography
    纯度
    > 90 % by SDS - PAGE
    Top Product
    Discover our top product OTC 蛋白
  • 说明

    Synonyms: ornithine carbamoyltransferase, OCTD, OTCase

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.5 mg/ml (determined by Bradford assay)
    缓冲液
    20 mM MES buffer (pH 6.0) containing 2 mM DTT, 10% glycerol, 100 mM NaCl
    储存条件
    4 °C
    储存方法
    Avoid repeated freezing and thawing cycles.
  • 抗原
    OTC (Ornithine Carbamoyltransferase (OTC))
    别名
    OTC (OTC 产品)
    别名
    OCTD Protein, 2810428A13Rik Protein, AA589422 Protein, AW457381 Protein, OCT Protein, Plxn2 Protein, mKIAA0463 Protein, F1B16.13 Protein, F1B16_13 Protein, ORNITHINE CARBAMOYLTRANSFERASE Protein, ornithine carbamoyltransferase Protein, BA4351 Protein, PSPTO4164 Protein, PLXN2 Protein, AI265390 Protein, Sf Protein, spf Protein, si:dkey-19h21.3 Protein, ornithine carbamoyltransferase Protein, plexin A2 Protein, ornithine carbamoyltransferase ArgF Protein, ornithine transcarbamylase Protein, OTC Protein, Plxna2 Protein, Otc Protein, argF Protein, argF-2 Protein, atpD-2 Protein, CNC04300 Protein, PLXNA2 Protein, otc Protein
    背景
    OTC, also called ornithine carbamoyltransferase, belongs to the ATCase/OTCase family. OTC plays a vital role in the urea cycle, catalyzing the second step in this pathway: the formation of L-citrulline from L-orthinine and carbamoyl phosphate. In humans, the urea cycle is an important pathway to detoxification of ammonia. Mutations in the gene encoding OTC are associated with the X-linked disorder OTCD (ornithine carbamoyltransferase deficiency). OTCD is a disorder of the urea cycle characterized by hyperammonemia. Recombinant human OTC protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
    分子量
    38.9kDa (347aa), confirmed by MALDI-TOF
    NCBI登录号
    NP_000522
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