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TTR Protein (AA 21-147) (His tag)

TTR 宿主: 人 宿主: 人细胞 Recombinant > 95 % as determined by reducing SDS-PAGE.
产品编号 ABIN1097694
发货至: 中国
  • 抗原 See all TTR 蛋白
    TTR (Transthyretin (TTR))
    蛋白类型
    Recombinant
    产品特性
    AA 21-147
    宿主
    • 11
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    资源
    • 20
    • 19
    • 7
    • 1
    • 1
    人细胞
    标记
    This TTR protein is labelled with His tag.
    原理
    Recombinant Human Transthyretin/TTR/PALB (C-6His)
    序列
    GPTGTGESKC PLMVKVLDAV RGSPAINVAV HVFRKAADDT WEPFASGKTS ESGELHGLTT EEEFVEGIYK VEIDTKSYWK ALGISPFHEH AEVVFTANDS GPRRYTIAAL LSPYSYSTTA VVTNPKEVDH HHHHH
    产品特性
    Recombinant Human Transthyretin/TTR produced by transfected human cells is a secreted protein with sequence (Gly21-Glu147) of Human TTR fused with a polyhistidine tag at the C-terminus.
    纯度
    > 95 % as determined by reducing SDS-PAGE.
    过滤
    0.2 μm filtered
    内毒素水平
    Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
    Top Product
    Discover our top product TTR 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    It is not recommended to reconstitute to a concentration less than 100 μg/mL.
    Dissolve the lyophilized protein in ddH2O.
    Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
    缓冲液
    Lyophilized from a 0.2 μm filtered solution of 20 mM TrisHCl, 150 mM NaCl, pH 8.0.
    注意事项
    Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
    储存条件
    4 °C/-20 °C/-80 °C
    储存方法
    Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
    Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
    Aliquots of reconstituted samples are stable at < -20°C for 3 months.
    有效期
    3 months
  • 抗原
    TTR (Transthyretin (TTR))
    别名
    transthyretin (TTR 产品)
    别名
    zgc:103583 Protein, TTR Protein, LOC100226992 Protein, CTS Protein, CTS1 Protein, HsT2651 Protein, PALB Protein, TBPA Protein, AA408768 Protein, AI787086 Protein, D17860 Protein, prealbumin Protein, Lr1 Protein, Tbpa Protein, Prealbumin Protein, xTTR Protein, transthyretin (prealbumin, amyloidosis type I) Protein, transthyretin Protein, Transthyretin Protein, transthyretin (prealbumin, amyloidosis type 1) Protein, transthyretin-like Protein, transthyretin L homeolog Protein, ttr Protein, TTR Protein, vpb38 Protein, MRAD2831_RS38185 Protein, Caci_4246 Protein, LOC100226992 Protein, Ttr Protein, ttr.L Protein
    Sub Type
    Fusionprotein
    背景
    Transthyretin is a secreted and cytoplasm protein which belongs to the Transthyretin family. Transthyretin is detected in serum and cerebrospinal fluid (at protein level). It is highly expressed in choroid plexus epithelial cells. It is also detected in retina pigment epithelium and liver. Each monomer of Transthyretin has two 4-stranded beta sheets and the shape of a prolate ellipsoid. Antiparallel beta-sheet interactions link monomers into dimers. A short loop from each monomer forms the main dimer-dimer interaction. These two pairs of loops separate the opposed, convex beta-sheets of the dimers to form an internal channel. Defects in Transthyretin are the cause of amyloidosis type 1 (AMYL1) which is a hereditary generalized amyloidosis due to transthyretin amyloid deposition. Protein fibrils can form in different tissues leading to amyloid polyneuropathies, amyloidotic cardiomyopathy, carpal tunnel syndrome, systemic senile amyloidosis. The disease includes leptomeningeal amyloidosis that is characterized by primary involvement of the central nervous system.
    Alternative Names: Transthyretin, ATTR, Prealbumin, TBPA, TTR, PALB
    分子量
    14.8 kDa
    UniProt
    P02766
    途径
    Hormone Transport
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