SERPINA5 Protein (AA 20-406) (His tag)
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- 抗原 See all SERPINA5 蛋白
- SERPINA5 (serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 5 (SERPINA5))
- 蛋白类型
- Recombinant
- 产品特性
- AA 20-406
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宿主
- 人
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资源
- 人细胞
- 标记
- This SERPINA5 protein is labelled with His tag.
- 原理
- Recombinant Human Serpin A5/Protein C Inhibitor (C-6His)
- 序列
- HRHHPREMKK RVEDLHVGAT VAPSSRRDFT FDLYRALASA APSQNIFFSP VSISMSLAML SLGAGSSTKM QILEGLGLNL QKSSEKELHR GFQQLLQELN QPRDGFQLSL GNALFTDLVV DLQDTFVSAM KTLYLADTFP TNFRDSAGAM KQINDYVAKQ TKGKIVDLLK NLDSNAVVIM VNYIFFKAKW ETSFNHKGTQ EQDFYVTSET VVRVPMMSRE DQYHYLLDRN LSCRVVGVPY QGNATALFIL PSEGKMQQVE NGLSEKTLRK WLKMFKKRQL ELYLPKFSIE GSYQLEKVLP SLGISNVFTS HADLSGISNH SNIQVSEMVH KAVVEVDESG TRAAAATGTI FTFRSARLNS QRLVFNRPFL MFIVDNNILF LGKVNRPVDH HHHHH
- 产品特性
- Recombinant Human Serpin A5 produced by transfected human cells is a secreted protein with sequence (His20-Pro406) of Human SERPINA5 fused with a polyhistidine tag at the C-terminus.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- 过滤
- 0.2 μm filtered
- 内毒素水平
- Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
- Top Product
- Discover our top product SERPINA5 蛋白
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serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 5 (SERPINA5) (AA 20-406) protein (His tag)
SERPINA5 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 5 (SERPINA5) (AA 17-406) protein (GST tag)SERPINA5 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 5 (SERPINA5) (AA 26-406) protein (His tag)Crystallography grade SERPINA5 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 5 (SERPINA5) (AA 25-405) protein (His tag)Crystallography grade SERPINA5 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 5 (SERPINA5) (AA 20-406) protein (His tag)SERPINA5 宿主: 人 宿主: Baculovirus infected Insect Cells Recombinant > 90 % by SDS - PAGE SDS
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
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It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles. - 缓冲液
- Lyophilized from a 0.2 μm filtered solution of 20 mM MES, 150 mM NaCl, pH 5.5.
- 注意事项
- Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
- 储存条件
- 4 °C/-20 °C/-80 °C
- 储存方法
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Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months. - 有效期
- 3 months
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- 抗原
- SERPINA5 (serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 5 (SERPINA5))
- 别名
- protein-c-inhibitor (SERPINA5 产品)
- 别名
- 4933415L04 Protein, PAI-3 Protein, Pci Protein, PAI3 Protein, PCI Protein, PCI-B Protein, PLANH3 Protein, PROCI Protein, serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 Protein, serpin family A member 5 Protein, serine (or cysteine) peptidase inhibitor, clade A, member 5 Protein, plasma serine protease inhibitor Protein, SPIA5 Protein, SERPINA5 Protein, Serpina5 Protein, LOC480424 Protein
- Sub Type
- Fusionprotein
- 背景
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Serpin A5 is a member of the human Serpin superfamily consists of at least 35 members. It is synthesized in the liver and has been detected in saliva, cerebral spinal fluid, amniotic fluid, tears and semen. As a potent inhibitor of the protein C anticoagulant pathway at the levels of both zymogen activation and enzyme inhibition, Serpin A5 additionally inhibits a variety of serine protease including thrombin, factor Xa, several kallekreins and acrosin. It plays a critical role in the processes of blood of blood coagulation and fertilization. Serpin A5 also inhibits urinary plasminogen activator (uPA), a mediator of tumor cell invasion, and regulates tumor growth and metastasis by inhibiting angiogenesis. Furthermore, recent studies have identified PCI as a potent and direct inhibitor of activated HGFA (hepatocyte growth factor activator), suggesting a novel function in the regulation of tissue repair and regeneration. Similar to Serpins C1 and D1, the thrombin inhibitory activity of serpinA5 is enhanced by heparin.
Alternative Names: Plasma Serine Protease Inhibitor, Acrosomal Serine Protease Inhibitor, Plasminogen Activator Inhibitor 3, PAI-3, PAI3, Protein C Inhibitor, PCI, Serpin A5, SERPINA5, PCI, PLANH3, PROCI - 分子量
- 44.7 kDa
- UniProt
- P05154
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