SERPINA12 Protein (AA 21-414) (GST tag)
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- 抗原 See all SERPINA12 蛋白
- SERPINA12 (serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 12 (SERPINA12))
- 蛋白类型
- Recombinant
- 产品特性
- AA 21-414
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宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 标记
- This SERPINA12 protein is labelled with GST tag.
- 原理
- Recombinant Human Serpin A12/Vaspin (N-GST)
- 序列
- MSPILGYWKI KGLVQPTRLL LEYLEEKYEE HLYERDEGDK WRNKKFELGL EFPNLPYYID GDVKLTQSMA IIRYIADKHN MLGGCPKERA EISMLEGAVL DIRYGVSRIA YSKDFETLKV DFLSKLPEML KMFEDRLCHK TYLNGDHVTH PDFMLYDALD VVLYMDPMCL DAFPKLVCFK KRIEAIPQID KYLKSSKYIA WPLQGWQATF GGGDHPPKSD LVPRGSLKPS FSPRNYKALS EVQGWKQRMA AKELARQNMD LGFKLLKKLA FYNPGRNIFL SPLSISTAFS MLCLGAQDST LDEIKQGFNF RKMPEKDLHE GFHYIIHELT QKTQDLKLSI GNTLFIDQRL QPQRKFLEDA KNFYSAETIL TNFQNLEMAQ KQINDFISQK THGKINNLIE NIDPGTVMLL ANYIFFRARW KHEFDPNVTK EEDFFLEKNS SVKVPMMFRS GIYQVGYDDK LSCTILEIPY QKNITAIFIL PDEGKLKHLE KGLQVDTFSR WKTLLSRRVV DVSVPRLHMT GTFDLKKTLS YIGVSKIFEE HGDLTKIAPH RSLKVGEAVH KAELKMDERG TEGAAGTGAQ TLPMETPLVV KIDKPYLLLI YSEKIPSVLF LGKIVNPIGK
- 产品特性
- Recombinant Human Serpin A12 is produced by our E. coli expression system. The target protein is expressed with sequence (Leu21-Lys414) of Human Serpin A12 fused with a GST tag at the N-terminus.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- 过滤
- 0.2 μm filtered
- 内毒素水平
- Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
- Top Product
- Discover our top product SERPINA12 蛋白
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serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 12 (SERPINA12) (AA 1-414) protein (GST tag)
SERPINA12 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 12 (SERPINA12) (AA 21-414) protein (His tag)Crystallography grade SERPINA12 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 12 (SERPINA12) (AA 21-413) protein (His tag)Crystallography grade SERPINA12 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
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- 限制
- 仅限研究用
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- 状态
- Liquid
- 溶解方式
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It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles. - 缓冲液
- Supplied as a 0.2 μm filtered solution of 50 mM TrisHCl, 160 mM NaCl, 0.2 mM PMSF, 1 mM DTT, 10 % Glycerine, pH 7.2 .
- 储存液
- Dithiothreitol (DTT)
- 注意事项
- This product contains Dithiothreitol (DTT): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
- 储存条件
- -80 °C
- 储存方法
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Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles. - 有效期
- 6 months
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- 抗原
- SERPINA12 (serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 12 (SERPINA12))
- 别名
- Serpin A12 (SERPINA12 产品)
- 别名
- SERPINA12 Protein, 4632419J12Rik Protein, OL-64 Protein, Ol-64 Protein, Ol64 Protein, serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 12 Protein, serpin family A member 12 Protein, serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 12 Protein, serpin A12 Protein, SERPINA12 Protein, Serpina12 Protein, LOC612386 Protein
- Sub Type
- Fusionprotein
- 背景
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Vaspin (Visceral Adipose-Specific SERPIN) is a newly described adipokine. Vaspin has three beta-sheets, nine alpha-helices, and one central loop, the structure is part of the set of distinctive features that are descriptive of Serpin family members. Vaspin is also a unique insulin sensitizing adipocytokine in obesity. A recent publication indicates that Vaspin mRNA expression in visceral fat is positively correlated with BMI and percent of body fat. and could be associated with parameters of obesity, insulin resistance, and glucose metabolism. These findings suggest a potential clinical use for Vaspin in ameliorating certain aberrations seen in the obesity metabolic syndrome.
Alternative Names: Serpin A12, OL-64, Visceral Adipose Tissue-Derived Serine Protease Inhibitor, Vaspin, Visceral Adipose-Specific Serpin, SERPINA12 - 分子量
- 71.4 kDa
- UniProt
- Q8IW75
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