PDIA6 Protein (AA 20-440) (His tag)
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- 抗原 See all PDIA6 蛋白
- PDIA6 (Protein Disulfide Isomerase Family A, Member 6 (PDIA6))
- 蛋白类型
- Recombinant
- 产品特性
- AA 20-440
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宿主
- 人
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资源
- 人细胞
- 标记
- This PDIA6 protein is labelled with His tag.
- 原理
- Recombinant Human Protein Disulfide-Isomerase A6/PDIA6 (C-6His)
- 序列
- LYSSSDDVIE LTPSNFNREV IQSDSLWLVE FYAPWCGHCQ RLTPEWKKAA TALKDVVKVG AVDADKHHSL GGQYGVQGFP TIKIFGSNKN RPEDYQGGRT GEAIVDAALS ALRQLVKDRL GGRSGGYSSG KQGRSDSSSK KDVIELTDDS FDKNVLDSED VWMVEFYAPW CGHCKNLEPE WAAAASEVKE QTKGKVKLAA VDATVNQVLA SRYGIRGFPT IKIFQKGESP VDYDGGRTRS DIVSRALDLF SDNAPPPELL EIINEDIAKR TCEEHQLCVV AVLPHILDTG AAGRNSYLEV LLKLADKYKK KMWGWLWTEA GAQSELETAL GIGGFGYPAM AAINARKMKF ALLKGSFSEQ GINEFLRELS FGRGSTAPVG GGAFPTIVER EPWDGRDGEL PVEDDIDLSD VELDDLGKDE LVDHHHHHH
- 产品特性
- Recombinant Human Protein Disulfide-Isomerase A6/PDIA6 produced by transfected human cells is a secreted protein with sequence (Leu20-Leu440) of human PDIA6 fused with a polyhistidine tag at the C-terminus.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- 过滤
- 0.2 μm filtered
- 内毒素水平
- Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
- Top Product
- Discover our top product PDIA6 蛋白
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Protein Disulfide Isomerase Family A, Member 6 (PDIA6) (AA 1-440) protein (GST tag)
PDIA6 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Protein Disulfide Isomerase Family A, Member 6 (PDIA6) (AA 20-440) protein (His tag)Crystallography grade PDIA6 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Protein Disulfide Isomerase Family A, Member 6 (PDIA6) (AA 20-440) protein (His tag)Crystallography grade PDIA6 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Protein Disulfide Isomerase Family A, Member 6 (PDIA6) protein (Myc-DYKDDDDK Tag)PDIA6 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- 限制
- 仅限研究用
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- 状态
- Liquid
- 溶解方式
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It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles. - 缓冲液
- Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl, 150 mM NaCl, 10 % Glycerol, pH 8.0.
- 注意事项
- Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
- 储存条件
- -80 °C
- 储存方法
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Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles. - 有效期
- 6 months
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- 抗原
- PDIA6 (Protein Disulfide Isomerase Family A, Member 6 (PDIA6))
- 别名
- pdia6 (PDIA6 产品)
- 别名
- 1700015E05Rik Protein, AL023058 Protein, C77895 Protein, CaBP5 Protein, P5 Protein, Txndc7 Protein, ERP5 Protein, TXNDC7 Protein, CaBP1 Protein, pdi-p5 Protein, erp5 Protein, pdia6 Protein, pdip5 Protein, txndc7 Protein, protein disulfide isomerase family A member 6 Protein, protein disulfide isomerase associated 6 Protein, protein disulfide isomerase family A, member 6 Protein, protein disulfide isomerase family A member 6 L homeolog Protein, PDIA6 Protein, Pdia6 Protein, pdia6.L Protein
- Sub Type
- Fusionprotein
- 背景
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Protein Disulfide-Isomerase A6 (PDIA6) is a 48.5kDa protein that belongs to the protein disulfide isomerase family (PDI). PDIA6 is an enzyme in the endoplasmic reticulum in eukaryotes which catalyzes the formation and breakage of disulfide bonds between cysteine residues within proteins as they fold. The PDIA6 expressed in platelets, its functions as a chaperone that inhibits aggregation of misfolded proteins. PDIA6 is part a large chaperone multiprotein complex comprising DNAJB11, HSP90B1, HSPA5, HYOU, PDIA2, PDIA4, PDIA6, PPIB, SDF2L1, UGT1A1. PDIA6 also plays a role in platelet aggregation and activation by agonists such as convulxin, collagen and thrombin.
Alternative Names: Protein Disulfide-Isomerase A6, Endoplasmic Reticulum Protein 5, ER Protein 5, ERp5, Protein Disulfide Isomerase P5, Thioredoxin Domain-Containing Protein 7, PDIA6, ERP5, P5, TXNDC7 - 分子量
- 47.2 kDa
- UniProt
- Q15084
- 途径
- ER-Nucleus Signaling, Cell RedoxHomeostasis
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