电话:
400-7060-959
传真:
+86 10 56315212-8813
电子邮件:
orders@antibodies-online.cn

SLAMF6 Protein (AA 28-225) (His tag)

SLAMF6 宿主: 人 宿主: 人细胞 Recombinant > 95 % as determined by reducing SDS-PAGE.
产品编号 ABIN1097248
发货至: 中国
  • 抗原 See all SLAMF6 蛋白
    SLAMF6 (SLAM Family Member 6 (SLAMF6))
    蛋白类型
    Recombinant
    产品特性
    AA 28-225
    宿主
    • 17
    • 4
    • 1
    资源
    • 13
    • 2
    • 2
    • 2
    • 2
    • 1
    人细胞
    标记
    This SLAMF6 protein is labelled with His tag.
    原理
    Recombinant Human SLAM Family Member 6/SLAMF6/CD352/NTB-A (C-6His)
    序列
    LMVNGILGES VTLPLEFPAG EKVNFITWLF NETSLAFIVP HETKSPEIHV TNPKQGKRLN FTQSYSLQLS NLKMEDTGSY RAQISTKTSA KLSSYTLRIL RQLRNIQVTN HSQLFQNMTC ELHLTCSVED ADDNVSFRWE ALGNTLSSQP NLTVSWDPRI SSEQDYTCIA ENAVSNLSFS VSAQKLCEDV KIQYTDTKVD HHHHHH
    产品特性

    Recombinant Human SLAM Family Member 6/SLAMF6/CD352/NTB-A (C-6His)

    纯度
    > 95 % as determined by reducing SDS-PAGE.
    过滤
    0.2 μm filtered
    内毒素水平
    Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
    Top Product
    Discover our top product SLAMF6 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    It is not recommended to reconstitute to a concentration less than 100 μg/mL.
    Dissolve the lyophilized protein in ddH2O.
    Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
    缓冲液
    Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.2.
    注意事项
    Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
    储存条件
    4 °C/-20 °C/-80 °C
    储存方法
    Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
    Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
    Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原
    SLAMF6 (SLAM Family Member 6 (SLAMF6))
    别名
    SLAM Family Member 6/SLAMF6 (SLAMF6 产品)
    别名
    SLAMF6 Protein, CD352 Protein, KALI Protein, KALIb Protein, Ly108 Protein, NTB-A Protein, NTBA Protein, SF2000 Protein, KAL1 Protein, KAL1b Protein, RGD1561848 Protein, SLAM family member 6 Protein, SLAMF6 Protein, Slamf6 Protein
    背景
    Recombinant Human SLAM Family Member 6/SLAMF6 is produced with our mammalian expression system in human cells. The target protein is expressed with sequence (Gln22-Met226) of Human SLAMF6 fused with a polyhistidine tag at the C-terminus.
    SLAM Family Member 6 (SLAMF6) is a 60 kDa single-pass type I membrane protein that belongs to the SLAM subgroup of the CD2 family. Human SLAMF6/ NTB-A contains a 205 AA extracellular domain (ECD) with one Ig-like V-set and one Ig-like C2-set domain, a 21 AA transmembrane segment and an 84 AA cytoplasmic domain, with two immunoreceptor tyrosine-based switch motifs. SLAMF6 is a homodimer. SLAMF6 can interact with PTN6 and, upon phosphorylation, with PTN11 and SH2D1A/SAP. Phosphorylation-dependent NTB-A association with SAP is required for full production of IFN-γ by NK cells and independent of EAT-2 binding. It Triggers cytolytic activity only in natural killer cells (NK) expressing high surface densities of natural cytotoxicity receptors. On B cells, NTB-A modulates immunoglobulin class switching and the balance between tolerance and autoimmunity.
    分子量
    23.98 kDa
    UniProt
    Q96DU3
You are here:
客服