RTN4RL1 Protein (AA 25-419) (His tag)
RTN4RL1
宿主: 人
宿主: 人细胞
Recombinant
> 95 % as determined by reducing SDS-PAGE.
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- 抗原 See all RTN4RL1 蛋白
- RTN4RL1 (Reticulon 4 Receptor-Like 1 (RTN4RL1))
- 蛋白类型
- Recombinant
- 产品特性
- AA 25-419
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宿主
- 人
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资源
- 人细胞
- 标记
- This RTN4RL1 protein is labelled with His tag.
- 原理
- Recombinant Human Nogo-66 Receptor-Related 3/NgR3/RTN4RL1 (C-6His)
- 序列
- CPRDCVCYPA PMTVSCQAHN FAAIPEGIPV DSERVFLQNN RIGLLQPGHF SPAMVTLWIY SNNITYIHPS TFEGFVHLEE LDLGDNRQLR TLAPETFQGL VKLHALYLYK CGLSALPAGV FGGLHSLQYL YLQDNHIEYL QDDIFVDLVN LSHLFLHGNK LWSLGPGTFR GLVNLDRLLL HENQLQWVHH KAFHDLRRLT TLFLFNNSLS ELQGECLAPL GALEFLRLNG NPWDCGCRAR SLWEWLQRFR GSSSAVPCVS PGLRHGQDLK LLRAEDFRNC TGPASPHQIK SHTLTTTDRA ARKEHHSPHG PTRSKGHPHG PRPGHRKPGK NCTNPRNRNQ ISKAGAGKQA PELPDYAPDY QHKFSFDIMP TARPKRKGKC ARRTPIRAPS GVQQAVDHHH HHH
- 产品特性
- Recombinant Human Nogo-66 Receptor-Related Protein 3/NgR3 produced by transfected human cells is a secreted protein with sequence (Cys25-Ala419) of Human RTN4RL1 fused with a polyhistidine tag at the C-terminus.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- 过滤
- 0.2 μm filtered
- 内毒素水平
- Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
- Top Product
- Discover our top product RTN4RL1 蛋白
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
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It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles. - 缓冲液
- Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, 5 % Threhalose, pH 7.2.
- 注意事项
- Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
- 储存条件
- 4 °C/-20 °C/-80 °C
- 储存方法
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Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months. - 有效期
- 3 months
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- 抗原
- RTN4RL1 (Reticulon 4 Receptor-Like 1 (RTN4RL1))
- 别名
- ngr3 (RTN4RL1 产品)
- 别名
- NgRH2a Protein, rtn4rl1 Protein, RTN4RL1 Protein, MGC146480 Protein, Ngr3 Protein, Ngrh2 Protein, Ngrl2 Protein, NGRH2 Protein, NgR3 Protein, reticulon 4 receptor-like 1b Protein, reticulon 4 receptor like 1 Protein, reticulon 4 receptor-like 1 Protein, rtn4rl1b Protein, RTN4RL1 Protein, rtn4rl1 Protein, Rtn4rl1 Protein
- Sub Type
- Fusionprotein
- 背景
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Nogo-66 Receptor-Related Protein 3 (NgR3) has primary structures with NgR2 (NgRH1, NgRL3) and biochemical properties that are homologous to Nogo-66 receptor (NgR), and constitute a novel neuronal receptor protein family. NgR is GPI-anchored and contains eight leucine-rich repeats (LRR), it is the neuronal receptor for the myelin- associated proteins Nogo-A, OMgp (oligodendrocyte myelin glycoprotein), and MAG (myelin-associated glycoprotein) and mediates the inhibition of CNS axonal regeneration both in vitro and in vivo. NgR2 and NgR3 have similar structure and distinct but overlapping expression versus NgR. NgR2 can be metalloproteinase-cleaved to release a soluble ectodomain. NgR2 has also been shown to bind MAG, but ligands for NgR3 have not yet been determined. Mature huaman NgR3 shares 88%, 88%, 48% and 44% amino acid identity with mature mouse NgR3, rat NgR3, human NgRH1 and NgR, repectively.
Alternative Names: Reticulon-4 Receptor-Like 1, Nogo Receptor-Like 2, Nogo-66 Receptor Homolog 2, Nogo-66 Receptor-Related Protein 3, NgR3, RTN4RL1, NGRH2, NGRL2 - 分子量
- 45.49 kDa
- UniProt
- Q86UN2
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