MMP1 Protein (AA 20-469) (His tag)
-
- 抗原 See all MMP1 蛋白
- MMP1 (Matrix Metallopeptidase 1 (Interstitial Collagenase) (MMP1))
- 蛋白类型
- Recombinant
- 产品特性
- AA 20-469
-
宿主
- 人
-
资源
- 人细胞
- 标记
- This MMP1 protein is labelled with His tag.
- 原理
- Recombinant Human Matrix Metalloproteinase-1/MMP-1 (C-6His)
- 序列
- FPATLETQEQ DVDLVQKYLE KYYNLKNDGR QVEKRRNSGP VVEKLKQMQE FFGLKVTGKP DAETLKVMKQ PRCGVPDVAQ FVLTEGNPRW EQTHLTYRIE NYTPDLPRAD VDHAIEKAFQ LWSNVTPLTF TKVSEGQADI MISFVRGDHR DNSPFDGPGG NLAHAFQPGP GIGGDAHFDE DERWTNNFRE YNLHRVAAHE LGHSLGLSHS TDIGALMYPS YTFSGDVQLA QDDIDGIQAI YGRSQNPVQP IGPQTPKACD SKLTFDAITT IRGEVMFFKD RFYMRTNPFY PEVELNFISV FWPQLPNGLE AAYEFADRDE VRFFKGNKYW AVQGQNVLHG YPKDIYSSFG FPRTVKHIDA ALSEENTGKT YFFVANKYWR YDEYKRSMDP GYPKMIAHDF PGIGHKVDAV FMKDGFFYFF HGTRQYKFDP KTKRILTLQK ANSWFNCRKN VDHHHHHH
- 产品特性
- Recombinant Human Matrix Metalloproteinase-1/MMP-1 is produced with our mammalian expression system in human cells. The target protein is expressed with sequence (Phe20-Asn469) of Human MMP-1 fused with a polyhistidine tag at the C-terminus.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- 过滤
- 0.2 μm filtered
- 内毒素水平
- Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
- Top Product
- Discover our top product MMP1 蛋白
-
Matrix Metallopeptidase 1 (Interstitial Collagenase) (MMP1) (AA 23-215) protein (His tag)
MMP1 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Matrix Metallopeptidase 1 (Interstitial Collagenase) (MMP1) (AA 370-469) protein (GST tag)MMP1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Matrix Metallopeptidase 1 (Interstitial Collagenase) (MMP1) (AA 1-469) protein (GST tag)MMP1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
-
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 溶解方式
-
It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles. - 缓冲液
- Supplied as a 0.2 μm filtered solution of 20 mM MES, 150 mM NaCl, 0.05 % Brij35, pH 5.5.
- 注意事项
- Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
- 储存条件
- -80 °C
- 储存方法
-
Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles. - 有效期
- 6 months
-
- 抗原
- MMP1 (Matrix Metallopeptidase 1 (Interstitial Collagenase) (MMP1))
- 别名
- mmp-1 (MMP1 产品)
- 别名
- CLG Protein, CLGN Protein, Mmp1a Protein, CG4859 Protein, Dm1-MMP Protein, Dmel\\CG4859 Protein, MMP-1 Protein, MMP1 Protein, Mmp 1 Protein, dMMP1 Protein, dm1-MMP Protein, dmmp1 Protein, l(2)k04809 Protein, mmp1 Protein, Mmp1 Protein, Mcol-A Protein, Mcola Protein, col4 Protein, mmp18 Protein, Clgn Protein, matrix metallopeptidase 1 Protein, Matrix metalloproteinase 1 Protein, matrix metalloproteinase 1 Protein, matrix metallopeptidase 1 (interstitial collagenase) Protein, matrix metallopeptidase 1a (interstitial collagenase) Protein, matrix metallopeptidase 1 S homeolog Protein, interstitial collagenase Protein, matrix metallopeptidase 8 L homeolog Protein, MMP1 Protein, Mmp1 Protein, RB11133 Protein, Mmp1a Protein, mmp1.S Protein, LOC100727966 Protein, mmp8.L Protein
- Sub Type
- Fusionprotein
- 背景
-
Matrix Metalloproteinase-1 (MMP-1) is expressed by fibroblasts, keratinocytes, endothelial cells, monocytes and macrophages. MMP1 contains several distinct domains: a prodomain that is cleaved upon activation, a catalytic domain containing the zinc binding site, a short hinge region, and a carboxyl terminal (hemopexin like) domain. MMP-1 can degrade a broad range of substrates including types I, II, III, VII, VIII, and X collagens as well as casein, gelatin, alpha1 antitrypsin, myelin basic protein, L-Selectin, pro-TNF, IL1, IGFBP3, IGFBP5, pro-MMP2, and pro-MMP9. A significant role of MMP1 is the degradation of fibrillar collagens in extracellular matrix remodeling, characterized by the cleavage of the interstitial collagen triple helix into 3/4, 1/4 fragments. MMP1 may also be involved in enzyme cascades, cytokine regulation and cell surface molecule modulation.
Alternative Names: Interstitial Collagenase, Fibroblast Collagenase, Matrix Metalloproteinase-1, MMP-1, MMP1, CLG - 分子量
- 52.88 kDa
- UniProt
- P03956
-
