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LUM Protein (AA 19-338) (His tag)

LUM 宿主: 人 宿主: 人细胞 Recombinant > 95 % as determined by reducing SDS-PAGE.
产品编号 ABIN1097110
发货至: 中国
  • 抗原 See all LUM 蛋白
    LUM (Lumican (LUM))
    蛋白类型
    Recombinant
    产品特性
    AA 19-338
    宿主
    • 7
    • 4
    • 1
    • 1
    • 1
    • 1
    资源
    • 4
    • 4
    • 2
    • 2
    • 2
    • 1
    人细胞
    标记
    This LUM protein is labelled with His tag.
    原理
    Recombinant Human Lumican/LUM (C-6His)
    序列
    QYYDYDFPLS IYGQSSPNCA PECNCPESYP SAMYCDELKL KSVPMVPPGI KYLYLRNNQI DHIDEKAFEN VTDLQWLILD HNLLENSKIK GRVFSKLKQL KKLHINHNNL TESVGPLPKS LEDLQLTHNK ITKLGSFEGL VNLTFIHLQH NRLKEDAVSA AFKGLKSLEY LDLSFNQIAR LPSGLPVSLL TLYLDNNKIS NIPDEYFKRF NALQYLRLSH NELADSGIPG NSFNVSSLVE LDLSYNKLKN IPTVNENLEN YYLEVNQLEK FDIKSFCKIL GPLSYSKIKH LRLDGNRISE TSLPPDMYEC LRVANEVTLN VDHHHHHH
    产品特性
    Recombinant Human Lumican/LUM produced by transfected human cells is a secreted protein with sequence (Gln19-Asn338) of Human Lumican fused with a polyhistidine tag at the C-terminus.
    纯度
    > 95 % as determined by reducing SDS-PAGE.
    过滤
    0.2 μm filtered
    内毒素水平
    Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
    Top Product
    Discover our top product LUM 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    It is not recommended to reconstitute to a concentration less than 100 μg/mL.
    Dissolve the lyophilized protein in ddH2O.
    Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
    缓冲液
    Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, 1 mM EDTA, pH 7.2.
    注意事项
    Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
    储存条件
    4 °C/-20 °C/-80 °C
    储存方法
    Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
    Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
    Aliquots of reconstituted samples are stable at < -20°C for 3 months.
    有效期
    3 months
  • 抗原
    LUM (Lumican (LUM))
    别名
    lumican (LUM 产品)
    别名
    MGC64527 Protein, zgc:86661 Protein, ldc Protein, slrr2d Protein, DKFZp468L1116 Protein, LDC Protein, SLRR2D Protein, Ldc Protein, lumican Protein, lumican L homeolog Protein, LUM Protein, lum.L Protein, lum Protein, CpipJ_CPIJ010209 Protein, Lum Protein
    Sub Type
    Fusionprotein
    背景
    Lumican is a 40 kD secreted protein which belongs to the small leucine-rich repeat proteoglycans (SLRPs) and the class II subfamily. Human Lumican is synthesized as a 338 amino acid precursor then cut the 18 aa signal sequence. The mature Human Lumican contains 12 leucine-rich repeats (LRRs), 4 potential sites of N-linked glycosylation, and a C- terminal with two conserved cyst-eines. Lumican can be existed in extracellular matrix of human articular cartilage. Lumican participates in the maintenance of tissue homeostasis and regulates cellular functions in vivo, such as cell proliferation, adhesion, migration, and differentiation. The overexpression of lumican has been correlated to colorectal tumor, breast, neuroendocrine, and pancreatic cancers.
    Alternative Names: Lumican, Keratan Sulfate Proteoglycan Lumican, KSPG Lumican, LUM, LDC, SLRR2D
    分子量
    37.7 kDa
    UniProt
    P51884
    途径
    Glycosaminoglycan Metabolic Process
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