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Oncostatin M Receptor Protein (OSMR) (AA 28-739) (His tag)

OSMR 宿主: 人 宿主: 人细胞 Recombinant > 95 % as determined by reducing SDS-PAGE.
产品编号 ABIN1096939
发货至: 中国
  • 抗原 See all Oncostatin M Receptor (OSMR) 蛋白
    Oncostatin M Receptor (OSMR)
    蛋白类型
    Recombinant
    产品特性
    AA 28-739
    宿主
    • 15
    • 6
    • 2
    • 1
    • 1
    资源
    • 11
    • 6
    • 4
    • 2
    • 1
    人细胞
    标记
    This Oncostatin M Receptor protein is labelled with His tag.
    原理
    Recombinant Human Oncostatin-M-Specific Receptor Subunit β/OSMRB/IL-31RB (C-6His)
    序列
    ERLPLTPVSL KVSTNSTRQS LHLQWTVHNL PYHQELKMVF QIQISRIETS NVIWVGNYST TVKWNQVLHW SWESELPLEC ATHFVRIKSL VDDAKFPEPN FWSNWSSWEE VSVQDSTGQD ILFVFPKDKL VEEGTNVTIC YVSRNIQNNV SCYLEGKQIH GEQLDPHVTA FNLNSVPFIR NKGTNIYCEA SQGNVSEGMK GIVLFVSKVL EEPKDFSCET EDFKTLHCTW DPGTDTALGW SKQPSQSYTL FESFSGEKKL CTHKNWCNWQ ITQDSQETYN FTLIAENYLR KRSVNILFNL THRVYLMNPF SVNFENVNAT NAIMTWKVHS IRNNFTYLCQ IELHGEGKMM QYNVSIKVNG EYFLSELEPA TEYMARVRCA DASHFWKWSE WSGQNFTTLE AAPSEAPDVW RIVSLEPGNH TVTLFWKPLS KLHANGKILF YNVVVENLDK PSSSELHSIP APANSTKLIL DRCSYQICVI ANNSVGASPA SVIVISADPE NKEVEEERIA GTEGGFSLSW KPQPGDVIGY VVDWCDHTQD VLGDFQWKNV GPNTTSTVIS TDAFRPGVRY DFRIYGLSTK RIACLLEKKT GYSQELAPSD NPHVLVDTLT SHSFTLSWKD YSTESQPGFI QGYHVYLKSK ARQCHPRFEK AVLSDGSECC KYKIDNPEEK ALIVDNLKPE SFYEFFITPF TSAGEGPSAT FTKVTTPDEH SSVDHHHHHH
    产品特性
    Recombinant Human Oncostatin-M-Specific Receptor Subunit beta/OSMRB produced by transfected human cells is a secreted protein with sequence (Glu28-Ser739) of Human OSMRB fused with a polyhistidine tag at the C-terminus.
    纯度
    > 95 % as determined by reducing SDS-PAGE.
    过滤
    0.2 μm filtered
    内毒素水平
    Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
    Top Product
    Discover our top product OSMR 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    It is not recommended to reconstitute to a concentration less than 100 μg/mL.
    Dissolve the lyophilized protein in ddH2O.
    Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
    缓冲液
    Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.2.
    注意事项
    Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
    储存条件
    4 °C/-20 °C/-80 °C
    储存方法
    Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
    Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
    Aliquots of reconstituted samples are stable at < -20°C for 3 months.
    有效期
    3 months
  • 抗原
    Oncostatin M Receptor (OSMR)
    别名
    Il-31-Rb (OSMR 产品)
    别名
    OSMRB Protein, PLCA1 Protein, oncostatin M receptor Protein, OSMR Protein, Osmr Protein
    Sub Type
    Fusionprotein
    背景
    Oncostatin-M-Specific Receptor Subunit beta (OSMRbeta) is a 150 - 180 kDa member of the IL-6 receptor family. OSMRbeta associates with gp130 to form the type II OSM receptor, the receptor is responsive to OSM. Gp130 subunit is shared by other IL-6 family cytokine receptors, and OSMRbeta associates with gp130-like receptor (GPL) to form a receptor complex responsive to IL-31. The human OSMRbeta cDNA encodes a 979 amino acid (aa) precursor, the precursor includes a 27 aa signal sequence, a 712 aa extracellular domain (ECD), a 22 aatransmembrane segment, and a 218 aa cytoplasmic domain. The ECD contains one partial and one complete hematopoietin domain, an Ig-like domain, and three Fibronectin type-III domains.
    Alternative Names: Oncostatin-M-Specific Receptor Subunit Beta, Interleukin-31 Receptor Subunit Beta, IL-31 Receptor Subunit Beta, IL-31R Subunit Beta, IL-31R-Beta, IL-31RB, OSMR, OSMRB
    分子量
    82.03 kDa
    UniProt
    Q99650
    途径
    JAK/STAT Signaling, Growth Factor Binding
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