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Glutathione Synthetase Protein (GSS) (AA 2-474) (His tag)

GSS 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 95 % as determined by reducing SDS-PAGE.
产品编号 ABIN1096753
发货至: 中国
  • 抗原 See all Glutathione Synthetase (GSS) 蛋白
    Glutathione Synthetase (GSS)
    蛋白类型
    Recombinant
    产品特性
    AA 2-474
    宿主
    • 6
    • 3
    • 3
    • 1
    • 1
    • 1
    资源
    • 9
    • 4
    • 1
    • 1
    大肠杆菌(E. Coli)
    标记
    This Glutathione Synthetase protein is labelled with His tag.
    原理
    Recombinant Human Glutathione Synthetase/GSH Synthetase (C-6His)
    序列
    ATNWGSLLQD KQQLEELARQ AVDRALAEGV LLRTSQEPTS SEVVSYAPFT LFPSLVPSAL LEQAYAVQMD FNLLVDAVSQ NAAFLEQTLS STIKQDDFTA RLFDIHKQVL KEGIAQTVFL GLNRSDYMFQ RSADGSPALK QIEINTISAS FGGLASRTPA VHRHVLSVLS KTKEAGKILS NNPSKGLALG IAKAWELYGS PNALVLLIAQ EKERNIFDQR AIENELLARN IHVIRRTFED ISEKGSLDQD RRLFVDGQEI AVVYFRDGYM PRQYSLQNWE ARLLLERSHA AKCPDIATQL AGTKKVQQEL SRPGMLEMLL PGQPEAVARL RATFAGLYSL DVGEEGDQAI AEALAAPSRF VLKPQREGGG NNLYGEEMVQ ALKQLKDSEE RASYILMEKI EPEPFENCLL RPGSPARVVQ CISELGIFGV YVRQEKTLVM NKHVGHLLRT KAIEHADGGV AAGVAVLDNP YPVLEHHHHH H
    产品特性
    Recombinant Human Glutathione Synthetase/GSS is produced by our E. coli expression system. The target protein is expressed with sequence (Ala2-Val474) of Human GSS fused with a 6His tag at the C-terminus.
    纯度
    > 95 % as determined by reducing SDS-PAGE.
    过滤
    0.2 μm filtered
    内毒素水平
    Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
    Top Product
    Discover our top product GSS 蛋白
  • 限制
    仅限研究用
  • 状态
    Liquid
    溶解方式
    It is not recommended to reconstitute to a concentration less than 100 μg/mL.
    Dissolve the lyophilized protein in ddH2O.
    Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
    缓冲液
    Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl, 200 mM NaCl, pH 7.5 .
    注意事项
    Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
    储存条件
    -80 °C
    储存方法
    Store at < -20°C, stable for 6 months after receipt.
    Please minimize freeze-thaw cycles.
    有效期
    6 months
  • 抗原
    Glutathione Synthetase (GSS)
    别名
    GSH-synthetase (GSS 产品)
    别名
    PRNP Protein, 6835 Protein, CG32497 Protein, CG33065 Protein, CG6835 Protein, Dmel\\CG6835 Protein, F21A20.90 Protein, F21A20_90 Protein, GLUTATHIONE SYNTHETASE Protein, GSHB Protein, glutathione synthetase 2 Protein, GSHS Protein, AI314904 Protein, GS-A/GS-B Protein, gssls-a Protein, glutathione synthetase Protein, Glutathione Synthetase Protein, glutathione synthetase 2 Protein, glutathione synthetase L homeolog Protein, GSS Protein, GSH2 Protein, Tola_1250 Protein, PC1_3711 Protein, Dd586_3633 Protein, Kvar_0701 Protein, Alvin_0197 Protein, Nhal_0215 Protein, BC1002_0254 Protein, Cseg_4017 Protein, Snov_3844 Protein, Aazo_1904 Protein, M301_2613 Protein, Bresu_0515 Protein, Isop_1460 Protein, Marme_4020 Protein, Thicy_0325 Protein, Sinme_3668 Protein, Mesop_0757 Protein, Gss Protein, gss.L Protein
    Sub Type
    Fusionprotein
    背景
    Glutathione Synthetase belongs to the eukaryotic GSH synthase family. Glutathione Synthetase is the second enzyme in the glutathione biosynthesis pathway. It catalyses the condensation of gamma-glutamylcysteine and glycine to form glutathione. Glutathione play an important role in a variety of biological functions, including detoxification of xenobiotics, protection of cells from oxidative damage by free radicals, and membrane transport. The protein functions as a homodimer to catalyze the second step of glutathione biosynthesis, which is the ATP-dependent conversion of gamma-L-glutamyl-L-cysteine to glutathione. Defects in Glutathione Synthetase can also cause the glutathione synthetase deficiency of erythrocytes, which is a mild form causing hemolytic anemia.
    Alternative Names: Glutathione Synthetase, GSH Synthetase, GSH-S, Glutathione Synthase, GSS
    分子量
    53.45 kDa
    UniProt
    P48637
    途径
    Warburg Effect
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