GNS Protein (AA 37-552) (His tag)
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- 抗原 See all GNS 蛋白
- GNS (Glucosamine (N-Acetyl)-6-Sulfatase (GNS))
- 蛋白类型
- Recombinant
- 产品特性
- AA 37-552
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宿主
- 人
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资源
- 人细胞
- 标记
- This GNS protein is labelled with His tag.
- 原理
- Recombinant Human N-Acetylglucosamine-6-Sulfatase/GNS (C-6His)
- 序列
- VFGVAAGTRR PNVVLLLTDD QDEVLGGMTP LKKTKALIGE MGMTFSSAYV PSALCCPSRA SILTGKYPHN HHVVNNTLEG NCSSKSWQKI QEPNTFPAIL RSMCGYQTFF AGKYLNEYGA PDAGGLEHVP LGWSYWYALE KNSKYYNYTL SINGKARKHG ENYSVDYLTD VLANVSLDFL DYKSNFEPFF MMIATPAPHS PWTAAPQYQK AFQNVFAPRN KNFNIHGTNK HWLIRQAKTP MTNSSIQFLD NAFRKRWQTL LSVDDLVEKL VKRLEFTGEL NNTYIFYTSD NGYHTGQFSL PIDKRQLYEF DIKVPLLVRG PGIKPNQTSK MLVANIDLGP TILDIAGYDL NKTQMDGMSL LPILRGASNL TWRSDVLVEY QGEGRNVTDP TCPSLSPGVS QCFPDCVCED AYNNTYACVR TMSALWNLQY CEFDDQEVFV EVYNLTADPD QITNIAKTID PELLGKMNYR LMMLQSCSGP TCRTPGVFDP GYRFDPRLMF SNRGSVRTRR FSKHLLVDHH HHHH
- 产品特性
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Recombinant Human N-Acetylglucosamine-6-Sulfatase/GNS (C-6His)
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- 过滤
- 0.2 μm filtered
- 内毒素水平
- Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
- Top Product
- Discover our top product GNS 蛋白
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Glucosamine (N-Acetyl)-6-Sulfatase (GNS) (AA 455-551) protein (GST tag)
GNS 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AA, AP
Glucosamine (N-Acetyl)-6-Sulfatase (GNS) (AA 1-552) protein (GST tag)GNS 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AA, AP
Glucosamine (N-Acetyl)-6-Sulfatase (GNS) protein (Myc-DYKDDDDK Tag)GNS 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- 限制
- 仅限研究用
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- 状态
- Liquid
- 溶解方式
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It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles. - 缓冲液
- Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl, 150 mM NaCl,10 % Glycerol, pH 8.0.
- 注意事项
- Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
- 储存条件
- -80 °C
- 储存方法
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Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles. - 有效期
- 6 months
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- 抗原
- GNS (Glucosamine (N-Acetyl)-6-Sulfatase (GNS))
- 别名
- N-Acetylglucosamine-6-Sulfatase/GNS (GNS 产品)
- 别名
- G6S Protein, 2610016K11Rik Protein, AU042285 Protein, C87209 Protein, N28088 Protein, NV14559 Protein, N-acetylglucosamine-6-sulfatase Protein, zgc:114066 Protein, gns Protein, wu:fi20h10 Protein, zgc:55370 Protein, glucosamine (N-acetyl)-6-sulfatase Protein, glucosamine (N-acetyl)-6-sulfatase S homeolog Protein, glucosamine (N-acetyl)-6-sulfatase a Protein, N-acetylglucosamine-6-sulfatase Protein, glucosamine (N-acetyl)-6-sulfatase (Sanfilippo disease IIID), b Protein, GNS Protein, Gns Protein, gns.S Protein, gns Protein, gnsa Protein, CpipJ_CPIJ000745 Protein, Sros_7372 Protein, VDBG_04409 Protein, Halhy_3165 Protein, gnsb Protein
- 背景
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Recombinant Human N-Acetylglucosamine-6-Sulfatase/GNS is produced by our mammalian expression system in human cells. The target protein is expressed with sequence (Val37-Leu552) of Human GNS fused with a polyhistidine tag at the C-terminus.
N-Acetylglucosamine-6-Sulfatase is a member of the Sulfatase family. N-Acetylglucosamine-6-Sulfatase is required for the lysosomal degradation of the Glycosaminoglycans (GAG) Heparan Sulfate and Keratan Sulfate. N-Acetylglucosamine-6-Sulfatase hydrolyzes the 6-Sulfate groups of the N-Acetyl-D-Glucosamine 6-Sulfate units of Heparan Sulfate and Keratan Sulfate. N-Acetylglucosamine-6-Sulfatase binds 1 Calcium ion per subunit. N-Acetylglucosamine-6-Sulfatase deficiency are the cause of Mucopolysaccharidosis Type 3D (MPS3D), an inborn error leading to lysosomal accumulation of heparan sulfate. MPS3D has profound mental deterioration, hyperactivity, and relatively mild somatic manifestations. - 分子量
- 59.35 kDa
- UniProt
- P15586
- 途径
- Glycosaminoglycan Metabolic Process
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