PSMD10 Protein (AA 1-226)
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- 抗原 See all PSMD10 蛋白
- PSMD10 (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 10 (PSMD10))
- 蛋白类型
- Recombinant
- 产品特性
- AA 1-226
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宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 原理
- Recombinant Human Gankyrin/PSDM10
- 序列
- MEGCVSNLMV CNLAYSGKLE ELKESILADK SLATRTDQDS RTALHWACSA GHTEIVEFLL QLGVPVNDKD DAGWSPLHIA ASAGRDEIVK ALLGKGAQVN AVNQNGCTPL HYAASKNRHE IAVMLLEGGA NPDAKDHYEA TAMHRAAAKG NLKMIHILLY YKASTNIQDT EGNTPLHLAC DEERVEEAKL LVSQGASIYI ENKEEKTPLQ VAKGGLGLIL KRMVEG
- 产品特性
- Recombinant Human Gankyrin is produced with our E. coli expression system. The target protein is expressed with sequence (Met1-Gly226) of Human PSMD10.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- 过滤
- 0.2 μm filtered
- 内毒素水平
- Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
- Top Product
- Discover our top product PSMD10 蛋白
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Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 10 (PSMD10) (AA 1-226) protein (GST tag)
PSMD10 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 10 (PSMD10) (AA 127-226) protein (GST tag)PSMD10 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 10 (PSMD10) (AA 1-226) protein (Strep Tag)Crystallography grade PSMD10 宿主: 人 宿主: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 10 (PSMD10) (AA 1-231) protein (Strep Tag)Crystallography grade PSMD10 宿主: 小鼠 宿主: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 10 (PSMD10) (Transcript Variant 1) proteinPSMD10 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 10 (PSMD10) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)PSMD10 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 10 (PSMD10) (Transcript Variant 2) protein (Myc-DYKDDDDK Tag)PSMD10 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- 限制
- 仅限研究用
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- 状态
- Liquid
- 溶解方式
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It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles. - 缓冲液
- Supplied as a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, 10 % Glycerol, pH 7.4.
- 注意事项
- Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
- 储存条件
- -80 °C
- 储存方法
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Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles. - 有效期
- 6 months
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- 抗原
- PSMD10 (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 10 (PSMD10))
- 别名
- gankyrin (PSMD10 产品)
- 别名
- gankyrin Protein, zgc:109707 Protein, dJ889N15.2 Protein, p28 Protein, p28(GANK) Protein, AW554874 Protein, p28Gank Protein, proteasome 26S subunit, non-ATPase 10 Protein, proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 Protein, psmd10 Protein, PSMD10 Protein, Psmd10 Protein
- 背景
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Gankyrin is a multicatalytic proteinase oncoprotein consists of 7 ankyrin repeats. Gankyrin overexpressed in most hepatocellular carcinomas. Gankyrin is involved in theregulation of the phosphorylation of the retinoblastoma protein by CDK4 to enhance the ubiquitinylation of p53 by MDM2. Gankyrin is also involved in progression of esophageal squamous cell carcinoma. Gankyrin plays an oncogenic role especially in early stages of human epatocarcinogenesis.
Alternative Names: 26S Proteasome Non-ATPase Regulatory Subunit 10, 26S Proteasome Regulatory Subunit p28, Gankyrin, p28(GANK), PSMD10 - 分子量
- 24.43 kDa
- UniProt
- O75832
- 途径
- Mitotic G1-G1/S Phases, DNA Replication, Maintenance of Protein Location, Synthesis of DNA, Ubiquitin Proteasome Pathway
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