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FETUB Protein (AA 16-382) (His tag)

FETUB 宿主: 人 宿主: 人细胞 Recombinant > 95 % as determined by reducing SDS-PAGE.
产品编号 ABIN1096645
发货至: 中国
  • 抗原 See all FETUB 蛋白
    FETUB (Fetuin B (FETUB))
    蛋白类型
    Recombinant
    产品特性
    AA 16-382
    宿主
    • 5
    • 4
    • 4
    • 3
    资源
    • 9
    • 2
    • 2
    • 1
    • 1
    • 1
    人细胞
    标记
    This FETUB protein is labelled with His tag.
    原理
    Recombinant Human Fetuin-B/FETUB (C-6His)
    序列
    CGAMSPPQLA LNPSALLSRG CNDSDVLAVA GFALRDINKD RKDGYVLRLN RVNDAQEYRR GGLGSLFYLT LDVLETDCHV LRKKAWQDCG MRIFFESVYG QCKAIFYMNN PSRVLYLAAY NCTLRPVSKK KIYMTCPDCP SSIPTDSSNH QVLEAATESL AKYNNENTSK QYSLFKVTRA SSQWVVGPSY FVEYLIKESP CTKSQASSCS LQSSDSVPVG LCKGSLTRTH WEKFVSVTCD FFESQAPATG SENSAVNQKP TNLPKVEESQ QKNTPPTDSP SKAGPRGSVQ YLPDLDDKNS QEKGPQEAFP VHLDLTTNPQ GETLDISFLF LEPMEEKLVV LPFPKEKART AECPGPAQNA SPLVLPPVDH HHHHH
    产品特性
    Recombinant Human Fetuin-B is produced with our mammalian expression system in human cells. The target protein is expressed with sequence (Cys16-Pro382) of Human FETUB fused with a polyhistidine tag at the C-terminus.
    纯度
    > 95 % as determined by reducing SDS-PAGE.
    过滤
    0.2 μm filtered
    内毒素水平
    Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
    Top Product
    Discover our top product FETUB 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    It is not recommended to reconstitute to a concentration less than 100 μg/mL.
    Dissolve the lyophilized protein in ddH2O.
    Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
    缓冲液
    Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.2.
    注意事项
    Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
    储存条件
    4 °C/-20 °C/-80 °C
    储存方法
    Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
    Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
    Aliquots of reconstituted samples are stable at < -20°C for 3 months.
    有效期
    3 months
  • 抗原
    FETUB (Fetuin B (FETUB))
    别名
    fetuin-b (FETUB 产品)
    别名
    16G2 Protein, Gugu Protein, IRL685 Protein, Fet Protein, Pp63 Protein, gugu Protein, fetuin-b Protein, FETUB Protein, 16g2 Protein, irl685 Protein, im:6910148 Protein, 2310011O17Rik Protein, AI255764 Protein, D17980 Protein, fetuin B Protein, fetuin B L homeolog Protein, fetuin beta Protein, FETUB Protein, Fetub Protein, fetub.L Protein, fetub Protein
    Sub Type
    Fusionprotein
    背景
    Fetuin-B is a member of the Fetuin family that is part of the Cystatin superfamily of Cysteine Protease inhibitors. It is reported that Fetuin-B is highly expressed in liver tissue, in tongue and placenta tissues. Fetuin-B is a paralogue of Fetuin-A. Fetuin-A and Fetuin-B display similarities and differences in their characteristics, however, they share only 20% amino acid sequence identity. The amounts of Fetuin-B in human serum, unlike Fetuin-A, vary with gender and are higher in females than in males. Fetuin-B is an inhibitor of basic calcium phosphate precipitation but is less active than Fetuin-A. Fetuin-B expression is decreased in Fetuin-A deficient knock-out mice. The expression of Fetuin-B has been shown to be regulated by FXR (Farnesoid X Receptor), a nuclear receptor activated by bile acids. Evidence has shown that overexpression of Fetuin-B in skin squamous carcinoma cells suppresses tumor growth in nude mice. The function of Fetuin B is still not fully characterized.
    Alternative Names: Fetuin-B, 16G2, Fetuin-Like Protein IRL685, Gugu, FETUB
    分子量
    41.53 kDa
    UniProt
    Q9UGM5
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