CXCL7 Protein (AA 59-128)
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- 抗原 See all CXCL7 (PPBP) 蛋白
- CXCL7 (PPBP) (Pro-Platelet Basic Protein (Chemokine (C-X-C Motif) Ligand 7) (PPBP))
- 蛋白类型
- Recombinant
- 生物活性
- Active
- 产品特性
- AA 59-128
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宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 应用范围
- Functional Studies (Func)
- 原理
- Recombinant Human C-X-C Motif Chemokine 7/CXCL7/NAP-2
- 序列
- AELRCMCIKT TSGIHPKNIQ SLEVIGKGTH CNQVEVIATL KDGRKICLDP DAPRIKKIVQ KKLAGDESAD
- 产品特性
- Recombinant Human C-X-C Motif Chemokine Ligand 7/CXCL7 produced in E. coli is a single non-glycosylated polypeptide chain containing 70 amino acids with a molecular mass of 7.6 kDa.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- 过滤
- 0.2 μm filtered
- 内毒素水平
- Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
- Top Product
- Discover our top product PPBP 蛋白
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Pro-Platelet Basic Protein (Chemokine (C-X-C Motif) Ligand 7) (PPBP) (AA 35-128) protein
PPBP 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 90 % by SDS - PAGE SDS
Pro-Platelet Basic Protein (Chemokine (C-X-C Motif) Ligand 7) (PPBP) (AA 35-128) protein (His tag)PPBP 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Pro-Platelet Basic Protein (Chemokine (C-X-C Motif) Ligand 7) (PPBP) (AA 1-128) protein (GST tag)PPBP 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Pro-Platelet Basic Protein (Chemokine (C-X-C Motif) Ligand 7) (PPBP) (AA 37-128) protein (GST tag)PPBP 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Pro-Platelet Basic Protein (Chemokine (C-X-C Motif) Ligand 7) (PPBP) (AA 59-125), (partial) protein (GST tag)PPBP 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant 90 % ELISA
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- 说明
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Biological activity: ED50 is 0.1-0.5 ng/mL as determined by the ability of Recombinant CXCL7 to chemoattract human CXCR2 transfected BaF3 mouse proB cells.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
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It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles. - 缓冲液
- Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.
- 注意事项
- Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
- 储存条件
- 4 °C/-20 °C/-80 °C
- 储存方法
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Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months. - 有效期
- 3 months
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- 抗原
- CXCL7 (PPBP) (Pro-Platelet Basic Protein (Chemokine (C-X-C Motif) Ligand 7) (PPBP))
- 别名
- Nap-2 (PPBP 产品)
- 别名
- 2400003M24Rik Protein, AI854500 Protein, CTAP3 Protein, CTAPIII Protein, Cxcl7 Protein, LA-PF4 Protein, LDGF Protein, MDGF Protein, NAP-2 Protein, NAP-2-L1 Protein, Scyb7 Protein, TGB Protein, TGB1 Protein, THBGB1 Protein, b-TG1 Protein, beta-TG Protein, B-TG1 Protein, Beta-TG Protein, CTAP-III Protein, CXCL7 Protein, PBP Protein, SCYB7 Protein, TC1 Protein, TC2 Protein, THBGB Protein, Nap-2 Protein, CTAPIII/NAP-2 Protein, Platelet basic protein Protein, pro-platelet basic protein Protein, scyb7 Protein, Ppbp Protein, PPBP Protein
- 背景
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Human Chemokine (C-X-C motif) Ligand 7 (CXCL7), also known as neutrophil activating peptide 2 (NAP-2), is a member of the CXC chemokines containing an ELR domain (Glu-Leu-Arg tripeptide motif). Similar to other ELR domain containing CXC chemokines, such as IL-8 and the GRO proteins, CXCL7 binds CXCR2, chemoattracts and activates neutrophils. CXCL7, Connective Tissue Activating Protein III (CTAPIII) and betathrombogulin (betaTG), are proteolytically processed carboxylterminal fragments of platelet basic protein (PBP) which is found in the alphagranules of human platelets. Although CTAPIII, betaTG, and PBP represent amino-terminal extended variants of NAP2 and possess the same CXC chemokine domains, these proteins do not exhibit CXCL7/NAP2 activity. CXCL7 induces cell migration through the G-protein-linked receptor CXCR-2.
Alternative Names: Platelet Basic Protein, PBP, C-X-C Motif Chemokine 7, Leukocyte-Derived Growth Factor, LDGF, Macrophage-Derived Growth Factor, MDGF Small-Inducible Cytokine B7, PPBP, CTAP3, CXCL7, SCYB7, TGB1, THBGB1 - 分子量
- 7.6 kDa
- UniProt
- P02775
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