CLIC4 Protein (AA 1-253) (His tag)
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- 抗原 See all CLIC4 蛋白
- CLIC4 (Chloride Intracellular Channel 4 (CLIC4))
- 蛋白类型
- Recombinant
- 产品特性
- AA 1-253
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宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 标记
- This CLIC4 protein is labelled with His tag.
- 原理
- Recombinant Human Chloride Intracellular Channel Protein 4/CLIC4 (N-6His)
- 序列
- MGSSHHHHHH SSGLVPRGSH MALSMPLNGL KEEDKEPLIE LFVKAGSDGE SIGNCPFSQR LFMILWLKGV VFSVTTVDLK RKPADLQNLA PGTHPPFITF NSEVKTDVNK IEEFLEEVLC PPKYLKLSPK HPESNTAGMD IFAKFSAYIK NSRPEANEAL ERGLLKTLQK LDEYLNSPLP DEIDENSMED IKFSTRKFLD GNEMTLADCN LLPKLHIVKV VAKKYRNFDI PKEMTGIWRY LTNAYSRDEF TNTCPSDKEV EIAYSDVAKR LTK
- 产品特性
- Recombinant Human Chloride Intracellular Channel Protein 4/CLIC4 produced by E. coli expression system. The target protein is expressed with sequence (Met1-Lys253) of Human CLIC4 fused with a 6His tag at the N-terminus.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- 过滤
- 0.2 μm filtered
- 内毒素水平
- Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
- Top Product
- Discover our top product CLIC4 蛋白
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Chloride Intracellular Channel 4 (CLIC4) (AA 1-253) protein (His tag)
CLIC4 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Chloride Intracellular Channel 4 (CLIC4) (AA 91-190) protein (GST tag)CLIC4 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Chloride Intracellular Channel 4 (CLIC4) protein (Myc-DYKDDDDK Tag)CLIC4 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- 限制
- 仅限研究用
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- 状态
- Liquid
- 溶解方式
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It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles. - 缓冲液
- Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl, 100 mM NaCl, 1 mM DTT, pH 8.0.
- 储存液
- Dithiothreitol (DTT)
- 注意事项
- This product contains Dithiothreitol (DTT): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
- 储存条件
- -80 °C
- 储存方法
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Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles. - 有效期
- 6 months
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- 抗原
- CLIC4 (Chloride Intracellular Channel 4 (CLIC4))
- 别名
- Chloride Intracellular Channel Protein 4/CLIC4 (CLIC4 产品)
- 别名
- CLIC4L Protein, H1 Protein, MTCLIC Protein, huH1 Protein, p64H1 Protein, cb142 Protein, wu:fb33c05 Protein, wu:fc30h10 Protein, clic4 Protein, MGC89006 Protein, CLIC4 Protein, DKFZp459A0325 Protein, D0Jmb3 Protein, TU-74 Protein, mc3s5 Protein, mtCLIC Protein, xclic4 Protein, chloride intracellular channel 4 Protein, chloride intracellular channel 4 (mitochondrial) Protein, chloride intracellular channel 4 S homeolog Protein, CLIC4 Protein, Clic4 Protein, clic4 Protein, clic4.S Protein
- Sub Type
- Fusionprotein
- 背景
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Chloride Intracellular Channel Protein 4 (CLIC4) is a 253 amino acid single-pass membrane protein that localizes to both the nucleus and the cytoplasm and contains one GST C-terminal domain. CLIC4 is expressed in various tissues and exhibits an intracellular vesicular pattern in Panc-1 cells (pancreatic cancer cells). CLIC4 acts as a monomer which is able to form selective ion channels in target proteins, thus facilitating the transport of chloride and other ions. CLIC4 is believed to have a role in apoptosis and is able to translocate to the nucleus under stress conditions. CLIC4 has alternate cellular functions like a potential role in angiogenesis or in maintaining apical-basolateral membrane polarity during mitosis and cytokinesis.
Alternative Names: Chloride Intracellular Channel Protein 4, Intracellular Chloride Ion Channel Protein p64H1, CLIC4 - 分子量
- 30.9 kDa
- UniProt
- Q9Y696
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