CD99 Protein (CD99) (AA 23-122) (His tag)
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- 抗原 See all CD99 蛋白
- CD99
- 蛋白类型
- Recombinant
- 产品特性
- AA 23-122
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宿主
- 人
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资源
- 人细胞
- 标记
- This CD99 protein is labelled with His tag.
- 原理
- Recombinant Human CD99/MIC2 (C-6His)
- 序列
- DGGFDLSDAL PDNENKKPTA IPKKPSAGDD FDLGDAVVDG ENDDPRPPNP PKPMPNPNPN HPSSSGSFSD ADLADGVSGG EGKGGSDGGG SHRKEGEEAD VDHHHHHH
- 产品特性
- Recombinant Human CD99 is produced with our mammalian expression system in human cells. The target protein is expressed with sequence (Asp23-Asp122) of Human CD99 fused with a polyhistidine tag at the C-terminus.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- 过滤
- 0.2 μm filtered
- 内毒素水平
- Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
- Top Product
- Discover our top product CD99 蛋白
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
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It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles. - 缓冲液
- Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.2.
- 注意事项
- Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
- 储存条件
- 4 °C/-20 °C/-80 °C
- 储存方法
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Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months. - 有效期
- 3 months
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- 抗原
- CD99
- 别名
- cd99 (CD99 产品)
- 别名
- 1110061M03Rik Protein, 2410026K10Rik Protein, D4 Protein, Pilr-l Protein, pilr-1 Protein, HBA71 Protein, MIC2 Protein, MIC2X Protein, MIC2Y Protein, MSK5X Protein, CD99 antigen Protein, CD99 molecule (Xg blood group) Protein, CD99 molecule Protein, Cd99 Protein, CD99 Protein
- Sub Type
- Fusionprotein
- 物质类
- Viral Protein
- 背景
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CD99 is a type I transmembrane glycoprotein and the founding member of the CD99 family of molecules. The extracellular domain of CD99 contains no identifiable motifs, its cytoplasmic region, although short, does have signal transduction capability. Cells known to express CD99 include fibroblasts, neutrophils, T cells, double positive thymocytes, CD34+ stem cells, monocytes and endothelial cells. Two types of CD99 isoforms have been classified. Native human CD99 is referred to as the long, or type I isoform. The best studied type II isoform shows an Asp-Gly substitution for the C terminal 27 amino acids. The type I and II isoforms have distinctive signal transduction pathways (FAKsrc for type I PI3K plus srcERK1/2 for type II), and mediate clearly different biological outcomes. Homophilic interaction between CD99 on the neutrophil and CD99 on the endothelial cell regulates the transendothelial migration of neutrophils during inflammation. Human CD99 has 48% aa sequence identity to mouse CD99.
Alternative Names: CD99 Antigen, 12E7, E2 Antigen, Protein MIC2, T-Cell Surface Glycoprotein E2, CD99, MIC2, MIC2X, MIC2Y - 分子量
- 11.13 kDa
- UniProt
- P14209
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