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CD177 Protein (AA 22-407) (His tag)

CD177 宿主: 人 宿主: 人细胞 Recombinant > 95 % as determined by reducing SDS-PAGE.
产品编号 ABIN1096299
发货至: 中国
  • 抗原 See all CD177 蛋白
    CD177 (CD177 Molecule (CD177))
    蛋白类型
    Recombinant
    产品特性
    AA 22-407
    宿主
    • 9
    • 2
    资源
    • 4
    • 4
    • 2
    • 1
    人细胞
    标记
    This CD177 protein is labelled with His tag.
    原理
    Recombinant Human PRV1/CD177(C-6His)
    序列
    LLCQFGTVQH VWKVSDLPRQ WTPKNTSCDS GLGCQDTLML IESGPQVSLV LSKGCTEAKD QEPRVTEHRM GPGLSLISYT FVCRQEDFCN NLVNSLPLWA PQPPADPGSL RCPVCLSMEG CLEGTTEEIC PKGTTHCYDG LLRLRGGGIF SNLRVQGCMP QPGCNLLNGT QEIGPVGMTE NCNRKDFLTC HRGTTIMTHG NLAQEPTDWT TSNTEMCEVG QVCQETLLLL DVGLTSTLVG TKGCSTVGAQ NSQKTTIHSA PPGVLVASYT HFCSSDLCNS ASSSSVLLNS LPPQAAPVPG DRQCPTCVQP LGTCSSGSPR MTCPRGTTHC YDGYIHLSGG GLSTKMSIQG CVAQPSSFLL NHTRQIGIFS AREKRDVQPP ASQHEGVDHH HHHH
    产品特性
    Recombinant Human CD177 is produced with our mammalian expression system in human cells. The target protein is expressed with sequence (Leu22-Gly407) of Human CD177 fused with a polyhistidine tag at the C-terminus.
    纯度
    > 95 % as determined by reducing SDS-PAGE.
    过滤
    0.2 μm filtered
    内毒素水平
    Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
    Top Product
    Discover our top product CD177 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    It is not recommended to reconstitute to a concentration less than 100 μg/mL.
    Dissolve the lyophilized protein in ddH2O.
    Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
    缓冲液
    Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.2.
    注意事项
    Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
    储存条件
    4 °C/-20 °C/-80 °C
    储存方法
    Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
    Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
    Aliquots of reconstituted samples are stable at < -20°C for 3 months.
    有效期
    3 months
  • 抗原
    CD177 (CD177 Molecule (CD177))
    别名
    cd177 (CD177 产品)
    别名
    HNA-2a Protein, HNA2A Protein, NB1 Protein, NB1 GP Protein, PRV-1 Protein, PRV1 Protein, RGD1562941 Protein, CD177 Protein, MGC157159 Protein, 1190003K14Rik Protein, Pdp3 Protein, CD177 molecule Protein, CD177 antigen Protein, CD177 Protein, Cd177 Protein
    Sub Type
    Fusionprotein
    背景
    CD177 is polymorphic and has at least two alleles: PRV1 and NB1. Human PRV1 is a Glycosyl-Phosphatidylinositol (GPI)-linked cell surface glycoprotein that belongs to the uPAR/CD59/Ly6 family of receptors. PRV1 is expressed by neutrophils and neutrophil precursors,and changes in expression serve as diagnostic markers for myeloproliferative disorders such as polycythemia vera and essential thrombocythemia. PRV1 may also be expressed by Erythroblasts, B cells, and Monocytes. NB1, a Glycosyl-Phosphatidylinositol (GPI)-linked cell surface glycoprotein, was first described in a case of neonatal alloimmune neutropenia. It is reported that CD177 functions as a novel heterophilic binding partner that engages PECAM-1 in membrane-proximal IgD6.
    Alternative Names: CD177 Antigen, Human Neutrophil Alloantigen 2a, HNA-2a, NB1 Glycoprotein, NB1 GP, Polycythemia Rubra Vera Protein 1, PRV-1, CD177, NB1, PRV1
    分子量
    42.33 kDa
    UniProt
    Q8N6Q3
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