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Cathepsin E Protein (CTSE) (AA 20-396) (His tag)

CTSE 宿主: 人 宿主: 人细胞 Recombinant > 95 % as determined by reducing SDS-PAGE.
产品编号 ABIN1096239
发货至: 中国
  • 抗原 See all Cathepsin E (CTSE) 蛋白
    Cathepsin E (CTSE)
    蛋白类型
    Recombinant
    产品特性
    AA 20-396
    宿主
    • 7
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    资源
    • 6
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    人细胞
    标记
    This Cathepsin E protein is labelled with His tag.
    原理
    Recombinant Human Cathepsin E/CTSE (C-6His)
    序列
    SLHRVPLRRH PSLKKKLRAR SQLSEFWKSH NLDMIQFTES CSMDQSAKEP LINYLDMEYF GTISIGSPPQ NFTVIFDTGS SNLWVPSVYC TSPACKTHSR FQPSQSSTYS QPGQSFSIQY GTGSLSGIIG ADQVSVEGLT VVGQQFGESV TEPGQTFVDA EFDGILGLGY PSLAVGGVTP VFDNMMAQNL VDLPMFSVYM SSNPEGGAGS ELIFGGYDHS HFSGSLNWVP VTKQAYWQIA LDNIQVGGTV MFCSEGCQAI VDTGTSLITG PSDKIKQLQN AIGAAPVDGE YAVECANLNV MPDVTFTING VPYTLSPTAY TLLDFVDGMQ FCSSGFQGLD IHPPAGPLWI LGDVFIRQFY SVFDRGNNRV GLAPAVPVDH HHHHH
    产品特性

    Recombinant Human Cathepsin E/CTSE (C-6His)

    Specific Activity is greater than 350pmol/min/ugMeasured by its ability to cleave the fluorogenic peptide substrate, Mca-PLGL-Dpa-AR-NH2

    纯度
    > 95 % as determined by reducing SDS-PAGE.
    过滤
    0.2 μm filtered
    内毒素水平
    Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
    Top Product
    Discover our top product CTSE 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    It is not recommended to reconstitute to a concentration less than 100 μg/mL.
    Dissolve the lyophilized protein in ddH2O.
    Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
    缓冲液
    Lyophilized from a 0.2 μm filtered solution of 20 mM MES, 150 mM NaCl, pH 5.5.
    注意事项
    Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
    储存条件
    4 °C/-20 °C/-80 °C
    储存方法
    Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
    Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
    Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原
    Cathepsin E (CTSE)
    别名
    Cathepsin E (CTSE 产品)
    别名
    CATE Protein, A430072O03Rik Protein, C920004C08Rik Protein, CE Protein, CatE Protein, CEA Protein, CEB Protein, Ctsea Protein, CTSE Protein, ce1 Protein, ce2 Protein, cate Protein, CE1 Protein, ce1-A Protein, ctse Protein, CE2 Protein, ce2-A Protein, cathepsin E Protein, cathepsin E L homeolog Protein, cathepsin E S homeolog Protein, CTSE Protein, Ctse Protein, TP03_0056 Protein, Smp_184930 Protein, ctse Protein, ctse.L Protein, ctse.S Protein
    背景
    Recombinant Human Cathepsin E is produced with our mammalian expression system in human cells. The target protein is expressed with sequence (Ser20-Pro396) of Human CTSE fused with a polyhistidine tag at the C-terminus.
    Cathepsin E (CTSE) is a gastric aspartyl protease that functions as a disulfide-linked homodimer. It is a member of the Peptidase C1 family, and has a specificity similar to that of Pepsin A and Cathepsin D. CTSE is localized to the endoplasmic reticulum and Golgi apparatus, while the mature enzyme is localized to the endosome. It is expressed abundantly in the stomach, the Clara cells of the lung and activated B-lymphocytes, and at lower levels in lymph nodes, skin and spleen. CTSE is an intracellular proteinase that have a role in immune function, activation-induced lymphocyte depletion in the thymus, neuronal degeneration and glial cell activation in the brain. Futhermore, it probably involved in the processing of antigenic peptides during MHC class II-mediated antigen presentation.
    分子量
    41.78 kDa
    UniProt
    P14091
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