CES1 Protein (AA 19-562) (His tag)
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- 抗原 See all CES1 蛋白
- CES1 (Carboxylesterase 1 (CES1))
- 蛋白类型
- Recombinant
- 产品特性
- AA 19-562
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宿主
- 人
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资源
- 人细胞
- 标记
- This CES1 protein is labelled with His tag.
- 原理
- Recombinant Human Carboxylesterase 1/CES1 (C-6His)
- 序列
- HPSSPPVVDT VHGKVLGKFV SLEGFAQPVA IFLGIPFAKP PLGPLRFTPP QPAEPWSFVK NATSYPPMCT QDPKAGQLLS ELFTNRKENI PLKLSEDCLY LNIYTPADLT KKNRLPVMVW IHGGGLMVGA ASTYDGLALA AHENVVVVTI QYRLGIWGFF STGDEHSRGN WGHLDQVAAL RWVQDNIASF GGNPGSVTIF GESAGGESVS VLVLSPLAKN LFHRAISESG VALTSVLVKK GDVKPLAEQI AITAGCKTTT SAVMVHCLRQ KTEEELLETT LKMKFLSLDL QGDPRESQPL LGTVIDGMLL LKTPEELQAE RNFHTVPYMV GINKQEFGWL IPMLMSYPLS EGQLDQKTAM SLLWKSYPLV CIAKELIPEA TEKYLGGTDD TVKKKDLFLD LIADVMFGVP SVIVARNHRD AGAPTYMYEF QYRPSFSSDM KPKTVIGDHG DELFSVFGAP FLKEGASEEE IRLSKMVMKF WANFARNGNP NGEGLPHWPE YNQKEGYLQI GANTQAAQKL KDKEVAFWTN LFAKKAVEKP PQTEVDHHHH HH
- 产品特性
- Recombinant Human Carboxylesterase 1/CES1 is produced with our mammalian expression system in human cells. The target protein is expressed with sequence (His19-Glu562) of Human CES1 fused with a polyhistidine tag at the C-terminus.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- 过滤
- 0.2 μm filtered
- 内毒素水平
- Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
- Top Product
- Discover our top product CES1 蛋白
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Carboxylesterase 1 (CES1) (AA 1-566) protein (GST tag)
CES1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Carboxylesterase 1 (CES1) (AA 18-567) protein (His tag)Crystallography grade CES1 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Carboxylesterase 1 (CES1) (AA 19-565) protein (His tag)Crystallography grade CES1 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Carboxylesterase 1 (CES1) (Transcript Variant 2) protein (His tag)CES1 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- 限制
- 仅限研究用
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- 状态
- Liquid
- 溶解方式
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It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles. - 缓冲液
- Supplied as a 0.2 μm filtered solution of 20 mM HAc-NaAc, 150 mM NaCl, pH 4.0.
- 注意事项
- Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
- 储存条件
- -80 °C
- 储存方法
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Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles. - 有效期
- 6 months
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- 抗原
- CES1 (Carboxylesterase 1 (CES1))
- 别名
- ces1 (CES1 产品)
- 别名
- ACAT Protein, CE-1 Protein, CEH Protein, CES2 Protein, HMSE Protein, HMSE1 Protein, PCE-1 Protein, REH Protein, SES1 Protein, TGH Protein, hCE-1 Protein, CESDD1 Protein, CES1 Protein, CES-K1 Protein, APLE Protein, PMPMEase Protein, CES Protein, carboxylesterase 1 Protein, liver carboxylesterase 1 Protein, liver carboxylesterase Protein, carboxylesterase 1 (monocyte/macrophage serine esterase 1) Protein, CES1 Protein, CpipJ_CPIJ013026 Protein, CpipJ_CPIJ016339 Protein, LOC100009551 Protein, LOC454097 Protein, LOC699486 Protein, LOC100050915 Protein
- Sub Type
- Fusionprotein
- 背景
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Carboxylesterase 1 (CES1) is a member of a large family of carboxylesterases that are responsible for the hydrolysis of ester and amide bonds. These enzymes have broad substrate specificity ranging from small molecule esters such as phenylester to long chain fatty acid esters and thioesters. They are major determinants of the pharmacokinetic behavior of most therapeutic agents containing an ester or amide bond. CES1 shares the serine hydrolase fold observed in other esterases. CES1 hydrolyzes aromatic and aliphatic esters, but has no catalytic activity toward amides or a fatty acyl-CoA ester. CES1 participates in detoxification of drugs such as cocaine and heroin in serum and liver. It may also play a role in detoxification in the lung and/or protection of the central nervous system from ester or amide compounds.
Alternative Names: Liver Carboxylesterase 1, Acyl-Coenzyme A:Cholesterol Acyltransferase, ACAT, Brain Carboxylesterase hBr1, Carboxylesterase 1, CE-1, hCE-1, Cocaine Carboxylesterase, Egasyn, HMSE, Methylumbelliferyl-Acetate Deacetylase 1, Monocyte/Macrophage Serine Esteras - 分子量
- 61.05 kDa
- 途径
- Monocarboxylic Acid Catabolic Process
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