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CDH6 Protein (AA 22-615) (His tag)

CDH6 宿主: 人 宿主: 人细胞 Recombinant > 95 % as determined by reducing SDS-PAGE.
产品编号 ABIN1096176
发货至: 中国
  • 抗原 See all CDH6 蛋白
    CDH6 (K-Cadherin (CDH6))
    蛋白类型
    Recombinant
    产品特性
    AA 22-615
    宿主
    • 11
    • 4
    • 2
    • 1
    • 1
    资源
    • 9
    • 3
    • 3
    • 2
    • 1
    人细胞
    标记
    This CDH6 protein is labelled with His tag.
    原理
    Recombinant Human Cadherin-6/K-Cadherin/CDH6 (C-6His)
    序列
    TPLSKRTSGF PAKKRALELS GNSKNELNRS KRSWMWNQFF LLEEYTGSDY QYVGKLHSDQ DRGDGSLKYI LSGDGAGDLF IINENTGDIQ ATKRLDREEK PVYILRAQAI NRRTGRPVEP ESEFIIKIHD INDNEPIFTK EVYTATVPEM SDVGTFVVQV TATDADDPTY GNSAKVVYSI LQGQPYFSVE SETGIIKTAL LNMDRENREQ YQVVIQAKDM GGQMGGLSGT TTVNITLTDV NDNPPRFPQS TYQFKTPESS PPGTPIGRIK ASDADVGENA EIEYSITDGE GLDMFDVITD QETQEGIITV KKLLDFEKKK VYTLKVEASN PYVEPRFLYL GPFKDSATVR IVVEDVDEPP VFSKLAYILQ IREDAQINTT IGSVTAQDPD AARNPVKYSV DRHTDMDRIF NIDSGNGSIF TSKLLDRETL LWHNITVIAT EINNPKQSSR VPLYIKVLDV NDNAPEFAEF YETFVCEKAK ADQLIQTLHA VDKDDPYSGH QFSFSLAPEA ASGSNFTIQD NKDNTAGILT RKNGYNRHEM STYLLPVVIS DNDYPVQSST GTVTVRVCAC DHHGNMQSCH AEALIHPTGL STGAVDHHHH HH
    产品特性

    Recombinant Human Cadherin-6/K-Cadherin/CDH6 (C-6His)

    纯度
    > 95 % as determined by reducing SDS-PAGE.
    过滤
    0.2 μm filtered
    内毒素水平
    Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
    Top Product
    Discover our top product CDH6 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    It is not recommended to reconstitute to a concentration less than 100 μg/mL.
    Dissolve the lyophilized protein in ddH2O.
    Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
    缓冲液
    Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.2.
    注意事项
    Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
    储存条件
    4 °C/-20 °C/-80 °C
    储存方法
    Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
    Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
    Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原
    CDH6 (K-Cadherin (CDH6))
    别名
    Cadherin-6 (CDH6 产品)
    别名
    KCAD Protein, K-cadherin Protein, cad6 Protein, cadherin-6 Protein, CAD6 Protein, c-cad6B Protein, cadherin 6 Protein, Cdh6 Protein, CDH6 Protein
    背景
    Recombinant Human Cadherin-6 produced by transfected human cells is a secreted protein with sequence (Ser54-Ala615) of Human CDH6 fused with a polyhistidine tag at the C-terminus.
    Cadherin-6 (CDH6) is a type-II classic cadherin cell-cell adhesion molecules, which are expressed in graded or areal patterns, as well as layer-specific patterns, in the cortical plate. Human Cadherin-6 is synthesized as a 790 aa type I transmembrane glycoprotein that contains a 18 aa signal peptide, a 35 aa propeptide, a 562 aa extracellular region, a 21 aa transmembrane segment, and a 154 aa cytoplasmic domain. There are five cadherin domains of approximately 110 aa each in the extracellular region. Cadherin-6 has high expression in kidney, brain, and cerebellum, and may contribute to the formation of the segmental structure of the early brain, as well as the development of renal proximal tubules. Weak expression is also detected in lung, pancreas, gastric mucosa and cytotrophoblasts. As a classic cadherin, Cadherin-6 will form homodimers and promote intercellular adhesion with itself and, possibly, Cadherin-9 and -14.
    分子量
    67.43 kDa
    UniProt
    P55285
    途径
    Cell-Cell Junction Organization
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