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APOA1 Protein (AA 19-267) (His tag)

APOA1 宿主: 人 宿主: 人细胞 Recombinant > 95 % as determined by reducing SDS-PAGE.
产品编号 ABIN1096035
发货至: 中国
  • 抗原 See all APOA1 蛋白
    APOA1 (Apolipoprotein A-I (APOA1))
    蛋白类型
    Recombinant
    产品特性
    AA 19-267
    宿主
    • 17
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    资源
    • 26
    • 17
    • 6
    • 2
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    • 1
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    人细胞
    标记
    This APOA1 protein is labelled with His tag.
    原理
    Recombinant Human Apolipoprotein A1/ApoA1 (C-6His)
    序列
    RHFWQQDEPP QSPWDRVKDL ATVYVDVLKD SGRDYVSQFE GSALGKQLNL KLLDNWDSVT STFSKLREQL GPVTQEFWDN LEKETEGLRQ EMSKDLEEVK AKVQPYLDDF QKKWQEEMEL YRQKVEPLRA ELQEGARQKL HELQEKLSPL GEEMRDRARA HVDALRTHLA PYSDELRQRL AARLEALKEN GGARLAEYHA KATEHLSTLS EKAKPALEDL RQGLLPVLES FKVSFLSALE EYTKKLNTQV DHHHHHH
    产品特性
    Recombinant Human Apolipoprotein A1/APOA1 produced by transfected human cells is a secreted protein with sequence (R19-Q267) of Human APOA1 fused with a polyhistidine tag at the C-terminus.
    纯度
    > 95 % as determined by reducing SDS-PAGE.
    过滤
    0.2 μm filtered
    内毒素水平
    Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
    Top Product
    Discover our top product APOA1 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    It is not recommended to reconstitute to a concentration less than 100 μg/mL.
    Dissolve the lyophilized protein in ddH2O.
    Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
    缓冲液
    Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.2.
    注意事项
    Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
    储存条件
    4 °C/-20 °C/-80 °C
    储存方法
    Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
    Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
    Aliquots of reconstituted samples are stable at < -20°C for 3 months.
    有效期
    3 months
  • 抗原
    APOA1 (Apolipoprotein A-I (APOA1))
    别名
    ApoA1 (APOA1 产品)
    别名
    Alp-1 Protein, Apoa-1 Protein, Brp-14 Protein, Ltw-1 Protein, Lvtw-1 Protein, Sep-1 Protein, Sep-2 Protein, Sep2 Protein, apoA-I Protein, apoa Protein, apoa1 Protein, cb49 Protein, wu:fb33f01 Protein, zgc:103718 Protein, MGC64335 Protein, MGC89745 Protein, Apo-AI Protein, ApoA-I Protein, APOA1 Protein, LOC100136573 Protein, apoa-i Protein, ApoAI Protein, apolipoprotein A1 Protein, apolipoprotein A-I Protein, apolipoprotein A-Ia Protein, apolipoprotein A-I S homeolog Protein, apolipoprotein A4 Protein, APOA1 Protein, Apoa1 Protein, apoa1a Protein, apoa1.S Protein, apoa1 Protein, LOC100136573 Protein, apoa-i Protein, apoa4 Protein
    Sub Type
    Fusionprotein
    背景
    Apolipoprotein A1 (APOA1) is a secreted protein which belongs to the Apolipoprotein A1/A4/E family. APOA1 is the major protein component of high density lipoprotein (HDL) in plasma. APOA1 plays a critical role in various biological processes, such as Cholesterol metabolism, Lipid metabolism and transport, Steroid metabolism. APOA1 promotes cholesterol efflux from tissues to the liver and thus helps to clear cholesterol from arteries. Defects in this gene resulted in HDL deficiencies, including Tangier disease (TGD), systemic non-neuropathic amyloidosis, premature coronary artery disease, hepatosplenomegaly and progressive muscle wasting and weakness. In addition, ApoA-I is implicated in the anti-endotoxin function of HDL via interaction with lipopolysaccharide or endotoxin.
    Synonyms: Apolipoprotein A-I, Apo-AI, ApoA-I, Apolipoprotein A1, APOA1
    分子量
    30 kDa
    UniProt
    P02647
    途径
    Regulation of Lipid Metabolism by PPARalpha, Production of Molecular Mediator of Immune Response, Lipid Metabolism
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