IGF2R Protein (AA 2328-2491, partial) (GST tag)
(3 references)-
- 抗原 See all IGF2R 蛋白
- IGF2R (Insulin-Like Growth Factor 2 Receptor (IGF2R))
- 蛋白类型
- Recombinant
- 产品特性
- AA 2328-2491, partial
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宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 标记
- This IGF2R protein is labelled with GST tag.
- 应用范围
- ELISA
- 序列
- KKERRETVIS KLTTCCRRSS NVSYKYSKVN KEEETDENET EWLMEEIQLP PPRQGKEGQE NGHITTKSVK ALSSLHGDDQ DSEDEVLTIP EVKVHSGRGA GAESSHPVRN AQSNALQERE DDRVGLVRGE KARKGKSSSA QQKTVSSTKL VSFHDDSDED LLHI
- 产品特性
- Please inquire if you are interested in this recombinant protein expressed in E. coli, mammalien cells or by baculovirus infection. Be aware about differences in price and lead time.
- 纯度
- 90 %
- Top Product
- Discover our top product IGF2R 蛋白
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Insulin-Like Growth Factor 2 Receptor (IGF2R) (AA 2159-2491) protein (His-IF2DI Tag)
IGF2R 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 90 % by SDS-PAGE gel analyses WB, ELISA
Insulin-Like Growth Factor 2 Receptor (IGF2R) (AA 121-220) protein (GST tag)IGF2R 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Insulin-Like Growth Factor 2 Receptor (IGF2R) (AA 2328-2491) protein (His tag)Crystallography grade IGF2R 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Insulin-Like Growth Factor 2 Receptor (IGF2R) (AA 2317-2483) protein (His tag)Crystallography grade IGF2R 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
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- 说明
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The yeast protein expression system is the most economical and efficient eukaryotic system for secretion and intracellular expression. A protein expressed by the mammalian cell system is of very high-quality and close to the natural protein. But the low expression level, the high cost of medium and the culture conditions restrict the promotion of mammalian cell expression systems. The yeast protein expression system serve as a eukaryotic system integrate the advantages of the mammalian cell expression system. A protein expressed by yeast system could be modificated such as glycosylation, acylation, phosphorylation and so on to ensure the native protein conformation. It can be used to produce protein material with high added value that is very close to the natural protein. Our proteins produced by yeast expression system has been used as raw materials for downstream preparation of monoclonal antibodies.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 浓度
- 0.2-2 mg/mL
- 缓冲液
- Tris-based buffer, 50 % glycerol
- 注意事项
- Repeated freezing and thawing is not recommended. Store working aliquots at 4 °C for up to one week
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C for extended storage, conserve at -20 °C or -80 °C
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: "Genomic structure of the human M6P/IGF2 receptor." in: Mammalian genome : official journal of the International Mammalian Genome Society, Vol. 10, Issue 1, pp. 74-7, (1999) (PubMed).
: "The human cation-independent mannose 6-phosphate receptor. Cloning and sequence of the full-length cDNA and expression of functional receptor in COS cells." in: The Journal of biological chemistry, Vol. 263, Issue 5, pp. 2553-62, (1988) (PubMed).
: "Insulin-like growth factor II receptor as a multifunctional binding protein." in: Nature, Vol. 329, Issue 6137, pp. 301-7, (1987) (PubMed).
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: "Genomic structure of the human M6P/IGF2 receptor." in: Mammalian genome : official journal of the International Mammalian Genome Society, Vol. 10, Issue 1, pp. 74-7, (1999) (PubMed).
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- 抗原
- IGF2R (Insulin-Like Growth Factor 2 Receptor (IGF2R))
- 别名
- Cation-independent mannose-6-phosphate receptor protein (IGF2R 产品)
- 别名
- CD222 Protein, CIMPR Protein, M6P-R Protein, MPR1 Protein, MPRI Protein, AI661837 Protein, CI-MPR Protein, M6P/IGF2R Protein, Mpr300 Protein, mpri Protein, cd222 Protein, cimpr Protein, m6p-r Protein, insulin like growth factor 2 receptor Protein, insulin-like growth factor 2 receptor Protein, IGF2R Protein, Igf2r Protein, igf2r Protein
- 背景
- Transport of phosphorylated lysosomal enzymes from the Golgi complex and the cell surface to lysosomes. Lysosomal enzymes bearing phosphomannosyl residues bind specifically to mannose-6-phosphate receptors in the Golgi apparatus and the resulting receptor-ligand complex is transported to an acidic prelyosomal compartment where the low pH mediates the dissociation of the complex. This receptor also binds IGF2. Acts as a positive regulator of T-cell coactivation, by binding DPP4.
- 分子量
- 45.7 kD
- UniProt
- P20645
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