Follistatin Protein (FST) (AA 30-217)
-
- 抗原 See all Follistatin (FST) 蛋白
- Follistatin (FST)
- 蛋白类型
- Recombinant
- 生物活性
- Active
- 产品特性
- AA 30-217
-
宿主
- 人
-
资源
- Tobacco (Nicotiana benthamiana)
- 应用范围
- Western Blotting (WB), Cell Culture (CC)
- 序列
- HHHHHHGNCW LRQAKNGRCQ VLYKTELSKE ECCSTGRLST SWTEEDVNDN TLFKWMIFNG GAPNCIPCKE TCENVDCGPG KKCRMNKKNK PRCVCAPDCS NITWKGPVCG LDGKTYRNEC ALLKARCKEQ PELEVQYQGR CKKTCRDVFC PGSSTCVVDQ TNNAYCVTCN RICPEPASSE QYLCGNDGVT YSSACHLRKA TCLLGRSIGL AYEGKCIKAK SCEDIQCTGG KKCLWDFKVG RGRCSLCDEL CPDSKSDEPV CASDNATYAS ECAMKEAACS SGVLLEVKHS GSCN
- 特异性
- Serological Identification: The protein was electrophoresed under reducing condition on a 15 % SDS-polyacrylamide gel, transferred by electroblotting to a NC membrane and visualized by immune-detection with specific Follistatin antibody.
- 产品特性
-
Molecular Formula: C1350H2153N405O433S39
Isoelectric Point: 8.18
Extinction Coefficient: 1.28 - 内毒素水平
- < 0.04 EU/µg protein (LAL method)
- Top Product
- Discover our top product FST 蛋白
-
Follistatin (FST) (AA 30-344) protein (His tag)
FST 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Follistatin (FST) (AA 30-317) protein (His-IF2DI Tag)FST 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Follistatin (FST) (AA 1-344) protein (GST tag)FST 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Follistatin (FST) (Active) protein (His tag)FST 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 98 % as determined by SDS-PAGE Active
Follistatin (FST) (Active) protein (Fc Tag)FST 宿主: 小鼠 宿主: CHO Cells Recombinant > 90 % as determined by SDS-PAGE Active
-
- 说明
-
rhuman Follistatin isoform 2 is a polypeptide chain containing 217 amino acids (30-217 of P19883 FST_HUMAN). It has a predicted molecular mass of 32.3 kDa. Human recombinant protein expressed in Nicotiana benthamiana. It is produced by transient expression in non-transgenic plants and is purified by sequential chromatography (FPLC). This product contains no animal-derived components or impurities. Animal Free product. The protein was resolved by SDS polyacrylamide gel electrophoresis and the gel was stained with coomassie blue.
- 限制
- 仅限研究用
-
- 状态
- Lyophilized
- 溶解方式
- Lyophilized protein should be reconstituted in water to a concentration of 50 ng/µL. Optimal concentration should be determined for specific application and cell lines.
- 缓冲液
- Tris HCl 0.05M buffer at pH 7.4
- 储存条件
- 4 °C
-
- 抗原
- Follistatin (FST)
- 别名
- Follistatin (FST 产品)
- 别名
- CG12955 Protein, CG12956 Protein, CG33466 Protein, Dmel\\CG33466 Protein, Fol1 Protein, dFS Protein, dFol1 Protein, dfs Protein, fs Protein, FS Protein, foll Protein, xfs Protein, FST Protein, fst Protein, AL033346 Protein, FOL1 Protein, Fst-288 Protein, RATFOL1 Protein, cb446 Protein, fd07h10 Protein, fst1 Protein, wu:fd07h10 Protein, Follistatin Protein, follistatin Protein, follistatin L homeolog Protein, follistatin a Protein, Fs Protein, fst Protein, FST Protein, LOC100141662 Protein, fst.L Protein, Fst Protein, fsta Protein
- 背景
-
Synonyms: FS288, Activin-binding protein
Follistatin is a monomeric glycoprotein that binds to ligands of the TGF-beta superfamily and regulates their activity by inhibiting their access to signalling receptors. Follistatin received its name because it suppresses synthesis and secretion of follicle-stimulating hormone (FSH) from the pituitary gland. The follistatin gene localizes to chromosome 5q11.2. It is composed of a relatively small 6-kb genomic DNA consisting of six exons. There is an alternative splice site that generates two major species, a full-length version that encodes a 344-amino acid preprotein differing by a 27-amino acid sequence from its carboxy-shortened version of the 317-amino acid form missing exon 6. Prior to activation, follistatin, like myostatin, undergoes further posttranslational modification to lose another 29 amino acids by removal of the signal peptide that results in polypeptides of 315 (FS315), often referred to as the long isoform and 288 (FS288), called the short isoform. - 分子量
- 32.3 kDa
- 途径
- Negative Regulation of Hormone Secretion
-
