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Protein tyrosine Phosphatase, Receptor Type, J 抗体

(Protein tyrosine Phosphatase, Receptor Type, J (PTPRJ))
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes, including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region containing five fibronectin type III repeats, a single transmembrane region, and a single intracytoplasmic catalytic domain, and thus represents a receptor-type PTP. This protein is present in all hematopoietic lineages, and was shown to negatively regulate T cell receptor signaling possibly through interfering with the phosphorylation of Phospholipase C Gamma 1 and Linker for Activation of T Cells. This protein can also dephosphorylate the PDGF beta receptor, and may be involved in UV-induced signal transduction. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

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  • 抗原: PTPRJ
  • Primary
Catalog no. 产品 适用 宿主 / 克隆类型 应用 价格和交货时间
ABIN6579535
PTPRJ 抗体 (AA 861-910) PTPRJ · Primary Antibody 人, 大鼠, 小鼠 兔 Polyclonal
  • WB (Western Blotting: 所列应用)
  • IHC (Immunohistochemistry: 所列应用)
  • ELISA (ELISA: 所列应用)
  • IF (Immunofluorescence: 所列应用)
  • 100 μL
  • 50 μL
发货至: 中国
ABIN6874358
PTPRJ 抗体 (Biotin) PTPRJ · Primary Antibody 人 兔 Polyclonal
  • 100 μL
发货至: 中国
Primary Antibody
  • WB (Western Blotting: 所列应用)
  • IHC (Immunohistochemistry: 所列应用)
  • ELISA (ELISA: 所列应用)
  • IF (Immunofluorescence: 所列应用)
适用
人, 大鼠, 小鼠
宿主
兔
克隆形成能力
Polyclonal
标记
unconjugated
抗体亚型
IgG
抗原表位
AA 861-910
产品编号 ABIN6579535
100 μL (More quantities available)
发货至: 中国
获取报价
Primary Antibody
适用
人
宿主
兔
克隆形成能力
Polyclonal
标记
Biotin
产品编号 ABIN6874358

Latest Publications for our Protein tyrosine Phosphatase, Receptor Type, J 抗体

Bilotta, Dattilo, DAgostino, Belviso, Scalise, Bilotta, Gaudio, Paduano, Perrotti, Florio, Fusco, Iuliano, Trapasso: "A novel splice variant of the protein tyrosine phosphatase PTPRJ that encodes for a soluble protein involved in angiogenesis." in: Oncotarget, Vol. 8, Issue 6, pp. 10091-10102, (2018) (PubMed).

Spring, Fournier, Lapointe, Chabot, Roussy, Pommey, Stagg, Royal: "The protein tyrosine phosphatase DEP-1/PTPRJ promotes breast cancer cell invasion and metastasis." in: Oncogene, Vol. 34, Issue 44, pp. 5536-47, (2015) (PubMed).

Spring, Lapointe, Caron, Langlois, Royal: "Phosphorylation of DEP-1/PTPRJ on threonine 1318 regulates Src activation and endothelial cell permeability induced by vascular endothelial growth factor." in: Cellular signalling, Vol. 26, Issue 6, pp. 1283-93, (2014) (PubMed).

Rollin, Pouplard, Gratacap, Leroux, May, Aupart, Gouilleux-Gruart, Payrastre, Gruel: "Polymorphisms of protein tyrosine phosphatase CD148 influence FcγRIIA-dependent platelet activation and the risk of heparin-induced thrombocytopenia." in: Blood, Vol. 120, Issue 6, pp. 1309-16, (2012) (PubMed).

Ambarus, Krausz, van Eijk, Hamann, Radstake, Reedquist, Tak, Baeten: "Systematic validation of specific phenotypic markers for in vitro polarized human macrophages." in: Journal of immunological methods, Vol. 375, Issue 1-2, pp. 196-206, (2012) (PubMed).

Stepanek, Kalina, Draber, Skopcova, Svojgr, Angelisova, Horejsi, Weiss, Brdicka: "Regulation of Src family kinases involved in T cell receptor signaling by protein-tyrosine phosphatase CD148." in: The Journal of biological chemistry, Vol. 286, Issue 25, pp. 22101-12, (2011) (PubMed).

Llinàs, Lázaro, de Salort, Matesanz-Isabel, Sintes, Engel: "Expression profiles of novel cell surface molecules on B-cell subsets and plasma cells as analyzed by flow cytometry." in: Immunology letters, Vol. 134, Issue 2, pp. 113-21, (2010) (PubMed).

Cabezón, Sintes, Llinàs, Benitez-Ribas: "Analysis of HLDA9 mAbs on plasmacytoid dendritic cells." in: Immunology letters, Vol. 134, Issue 2, pp. 167-73, (2010) (PubMed).

Dong, Shahsafaei, Dorfman: "CD148 and CD27 are expressed in B cell lymphomas derived from both memory and naïve B cells." in: Leukemia & lymphoma, Vol. 43, Issue 9, pp. 1855-8, (2003) (PubMed).

Ruivenkamp, van Wezel, Zanon, Stassen, Vlcek, Csikós, Klous, Tripodis, Perrakis, Boerrigter, Groot, Lindeman, Mooi, Meijjer, Scholten, Dauwerse, Paces, van Zandwijk, van Ommen, Demant: "Ptprj is a candidate for the mouse colon-cancer susceptibility locus Scc1 and is frequently deleted in human cancers." in: Nature genetics, Vol. 31, Issue 3, pp. 295-300, (2002) (PubMed).

Aliases for Protein tyrosine Phosphatase, Receptor Type, J 抗体

acid phosphatase 1 (ACP1) 抗体
protein tyrosine phosphatase, receptor type J (PTPRJ) 抗体
protein tyrosine phosphatase, receptor type, J (Ptprj) 抗体
protein tyrosine phosphatase, receptor type, J (PTPRJ) 抗体
protein tyrosine phosphatase, receptor type, J (EUBREC_2762) 抗体
AI450271 抗体
BET 抗体
Byp 抗体
CD148 抗体
DEP-1 抗体
DEP1 抗体
HAAP 抗体
HPTPeta 抗体
Ptpb2 抗体
PTPbeta2 抗体
PTPRJ 抗体
R-PTP-ETA 抗体
RPTPJ 抗体
Scc-1 抗体
SCC1 抗体
Scc1 抗体
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