PRKAG3 抗体
(Protein Kinase, AMP-Activated, gamma 3 Non-Catalytic Subunit (PRKAG3))
The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit is one of the gamma regulatory subunits of AMPK. It is dominantly expressed in skeletal muscle. Studies of the pig counterpart suggest that this subunit may play a key role in the regulation of energy metabolism in skeletal muscle. [provided by RefSeq, Jul 2008].
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Latest Publications for our PRKAG3 抗体
: "Expression of 5'-AMP-activated protein kinase with starvation in murine thymocytes." in: The Bulletin of Tokyo Dental College, Vol. 52, Issue 1, pp. 21-9, (2011) (PubMed).: "Hypoxia induces expression and activation of AMPK in rat dental pulp cells." in: Journal of dental research, Vol. 86, Issue 9, pp. 903-7, (2007) (PubMed).
: "Gain-of-function R225W mutation in human AMPKgamma(3) causing increased glycogen and decreased triglyceride in skeletal muscle." in: PLoS ONE, Vol. 2, Issue 9, pp. e903, (2007) (PubMed).
Aliases for PRKAG3 抗体
protein kinase AMP-activated non-catalytic subunit gamma 3 (Prkag3) 抗体protein kinase AMP-activated non-catalytic subunit gamma 3 (PRKAG3) 抗体
protein kinase, AMP-activated, gamma 3 non-catalytic subunit S homeolog (prkag3.S) 抗体
protein kinase, AMP-activated, gamma 3 non-catatlytic subunit b (prkag3-b) 抗体
protein kinase, AMP-activated, gamma 3 non-catatlytic subunit (Prkag3) 抗体
Amkg3 抗体
Ampkg3 抗体
AMPKG3 抗体
AMPKg3L 抗体
AMPKg3S 抗体
PRKAG3 抗体
prkag3-a 抗体
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