PRKAG2 产品
(Protein Kinase, AMP-Activated, gamma 2 Non-Catalytic Subunit (PRKAG2))
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AMP-activated protein kinase (AMPK) is a heterotrimeric protein composed of a catalytic alpha subunit, a noncatalytic beta subunit, and a noncatalytic regulatory gamma subunit. Various forms of each of these subunits exist, encoded by different genes. AMPK is an important energy-sensing enzyme that monitors cellular energy status and functions by inactivating key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This gene is a member of the AMPK gamma subunit family and encodes a protein with four cystathionine beta-synthase domains. Mutations in this gene have been associated with ventricular pre-excitation (Wolff-Parkinson-White syndrome), progressive conduction system disease and cardiac hypertrophy. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008].
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Featured PRKAG2 Categories
Recommended PRKAG2 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IF, IP
Validations
- (4)
Cat. No.
ABIN526709
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, IHC (p)
Validations
- (1)
- (3)
Cat. No.
ABIN2856952
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IF
Validations
- (3)
Cat. No.
ABIN565604
Quantity
100 μg
Datasheet
Datasheet
Recommended PRKAG2 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1316235
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1316237
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3136803
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our PRKAG2 Products
: "Subunit composition of AMPK trimers present in the cytokinetic apparatus: Implications for drug target identification." in: Cell cycle (Georgetown, Tex.), Vol. 11, Issue 5, pp. 917-21, (2012) (PubMed).: "Functional dissection of lysine deacetylases reveals that HDAC1 and p300 regulate AMPK." in: Nature, Vol. 482, Issue 7384, pp. 251-5, (2012) (PubMed).
: "Generation of digital responses in stress sensors." in: The Journal of biological chemistry, Vol. 284, Issue 36, pp. 23902-11, (2009) (PubMed).
: "Molecular genetic analysis of PRKAG2 in sporadic Wolff-Parkinson-White syndrome." in: Journal of cardiovascular electrophysiology, Vol. 14, Issue 3, pp. 263-8, (2003) (PubMed).
: "Functional analysis of mutations in the gamma 2 subunit of AMP-activated protein kinase associated with cardiac hypertrophy and Wolff-Parkinson-White syndrome." in: The Journal of biological chemistry, Vol. 277, Issue 52, pp. 51017-24, (2002) (PubMed).
: "PRKAG2 cardiac syndrome: familial ventricular preexcitation, conduction system disease, and cardiac hypertrophy." in: Current opinion in cardiology, Vol. 17, Issue 3, pp. 229-34, (2002) (PubMed).
: "Fiber type-specific analysis of AMPK isoforms in human skeletal muscle: advancement in methods via capillary nano-immunoassay." in: Journal of applied physiology (Bethesda, Md. : 1985) (PubMed).
Synonyms and alternative names related to PRKAG2
protein kinase AMP-activated non-catalytic subunit gamma 2 (Prkag2), protein kinase AMP-activated non-catalytic subunit gamma 2 (PRKAG2), protein kinase, AMP-activated, gamma 2 non-catalytic subunit L homeolog (prkag2.L), 5'-AMP-activated protein kinase subunit gamma-2 (LOC504219), protein kinase, AMP-activated, gamma 2 non-catalytic subunit b (prkag2b), protein kinase, AMP-activated, gamma 2 non-catalytic subunit (prkag2), protein kinase, AMP-activated, gamma 2 non-catalytic subunit (Prkag2), 2410051C13Rik, AAKG, AAKG2, AI854673, CMH6, H91620p, MGC82938, PRKAG2, si:ch211-230l11.1, si:dkey-217f4.2, WPWSProtein level used designations for PRKAG2
- 5'-AMP-activated protein kinase subunit gamma-2
- AMP-activated protein kinase gamma2 subunit
- AMPK gamma 2
- adenosine monophosphate-activated protein kinase gamma 2-subunit
- 5'-AMP-activated protein kinase gamma-2 non-catalytic subunit
- protein kinase, AMP-activated, gamma 2 non-catalytic subunit
- AMPK-activated protein kinase gamma-2 subunit
- AMPK subunit gamma-2
- 5-AMP-activated protein kinase, gamma-2 subunit
- AMPK gamma-2 chain
- AMPK gamma2
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