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PRKAG2 产品

(Protein Kinase, AMP-Activated, gamma 2 Non-Catalytic Subunit (PRKAG2))

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AMP-activated protein kinase (AMPK) is a heterotrimeric protein composed of a catalytic alpha subunit, a noncatalytic beta subunit, and a noncatalytic regulatory gamma subunit. Various forms of each of these subunits exist, encoded by different genes. AMPK is an important energy-sensing enzyme that monitors cellular energy status and functions by inactivating key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This gene is a member of the AMPK gamma subunit family and encodes a protein with four cystathionine beta-synthase domains. Mutations in this gene have been associated with ventricular pre-excitation (Wolff-Parkinson-White syndrome), progressive conduction system disease and cardiac hypertrophy. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008].

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Featured PRKAG2 Categories

PRKAG2 抗体

High quality antibodies with extensive validation data.

PRKAG2 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended PRKAG2 抗体

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Reactivity
Application
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Cat. No.
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Datasheet
Reactivity Human
Application WB, IF, IP
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Cat. No. ABIN526709
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, IHC (p)
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  • (1)
  • (3)
Cat. No. ABIN2856952
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IF
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  • (3)
Cat. No. ABIN565604
Quantity 100 μg
Datasheet Datasheet

Recommended PRKAG2 蛋白

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Source
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Cat. No.
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Reactivity Human
Source Wheat germ
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Cat. No. ABIN1316237
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
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Cat. No. ABIN1316235
Quantity 10 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
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Cat. No. ABIN7405708
Quantity 100 μg
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Latest Publications for our PRKAG2 Products

Pinter, Jefferson, Czibik, Watkins, Redwood: "Subunit composition of AMPK trimers present in the cytokinetic apparatus: Implications for drug target identification." in: Cell cycle (Georgetown, Tex.), Vol. 11, Issue 5, pp. 917-21, (2012) (PubMed).

Lin, Kiihl, Suhail, Liu, Chou, Kuang, Lu, Khor, Lin, Bader, Irizarry, Boeke: "Functional dissection of lysine deacetylases reveals that HDAC1 and p300 regulate AMPK." in: Nature, Vol. 482, Issue 7384, pp. 251-5, (2012) (PubMed).

Martiáñez, Francès, López: "Generation of digital responses in stress sensors." in: The Journal of biological chemistry, Vol. 284, Issue 36, pp. 23902-11, (2009) (PubMed).

Vaughan, Hom, Okin, McDermott, Lerman, Basson: "Molecular genetic analysis of PRKAG2 in sporadic Wolff-Parkinson-White syndrome." in: Journal of cardiovascular electrophysiology, Vol. 14, Issue 3, pp. 263-8, (2003) (PubMed).

Daniel, Carling: "Functional analysis of mutations in the gamma 2 subunit of AMP-activated protein kinase associated with cardiac hypertrophy and Wolff-Parkinson-White syndrome." in: The Journal of biological chemistry, Vol. 277, Issue 52, pp. 51017-24, (2002) (PubMed).

Gollob, Green, Tang, Roberts: "PRKAG2 cardiac syndrome: familial ventricular preexcitation, conduction system disease, and cardiac hypertrophy." in: Current opinion in cardiology, Vol. 17, Issue 3, pp. 229-34, (2002) (PubMed).

Tobias, Lazauskas, Arevalo, Bagley, Brown, Galpin: "Fiber type-specific analysis of AMPK isoforms in human skeletal muscle: advancement in methods via capillary nano-immunoassay." in: Journal of applied physiology (Bethesda, Md. : 1985) (PubMed).

Synonyms and alternative names related to PRKAG2

protein kinase AMP-activated non-catalytic subunit gamma 2 (Prkag2), protein kinase AMP-activated non-catalytic subunit gamma 2 (PRKAG2), protein kinase, AMP-activated, gamma 2 non-catalytic subunit L homeolog (prkag2.L), 5'-AMP-activated protein kinase subunit gamma-2 (LOC504219), protein kinase, AMP-activated, gamma 2 non-catalytic subunit b (prkag2b), protein kinase, AMP-activated, gamma 2 non-catalytic subunit (prkag2), protein kinase, AMP-activated, gamma 2 non-catalytic subunit (Prkag2), 2410051C13Rik, AAKG, AAKG2, AI854673, CMH6, H91620p, MGC82938, PRKAG2, si:ch211-230l11.1, si:dkey-217f4.2, WPWS

Protein level used designations for PRKAG2

  • 5'-AMP-activated protein kinase subunit gamma-2
  • AMP-activated protein kinase gamma2 subunit
  • AMPK gamma 2
  • adenosine monophosphate-activated protein kinase gamma 2-subunit
  • 5'-AMP-activated protein kinase gamma-2 non-catalytic subunit
  • protein kinase, AMP-activated, gamma 2 non-catalytic subunit
  • AMPK-activated protein kinase gamma-2 subunit
  • AMPK subunit gamma-2
  • 5-AMP-activated protein kinase, gamma-2 subunit
  • AMPK gamma-2 chain
  • AMPK gamma2
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