PRKAG1 产品
(Protein Kinase, AMP-Activated, gamma 1 Non-Catalytic Subunit (PRKAG1))
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The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit is one of the gamma regulatory subunits of AMPK. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008].
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Featured PRKAG1 Categories
Recommended PRKAG1 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
ELISA, IHC, ICC, FACS
Validations
- (2)
- (7)
Cat. No.
ABIN1724932
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (4)
Cat. No.
ABIN7439723
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
IHC, IF
Validations
- (4)
Cat. No.
ABIN7263301
Quantity
200 μL
Datasheet
Datasheet
Recommended PRKAG1 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (3)
Cat. No.
ABIN7551868
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Mouse
Source
HEK-293 Cells
Validations
- (3)
Cat. No.
ABIN7562453
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1316233
Quantity
10 μg
Datasheet
Datasheet
Latest Publications for our PRKAG1 Products
: "AMP-activated protein kinase regulation and biological actions in the heart." in: Circulation research, Vol. 111, Issue 6, pp. 800-14, (2012) (PubMed).: "AMP-activated protein kinase phosphorylates cardiac troponin I and alters contractility of murine ventricular myocytes." in: Circulation research, Vol. 110, Issue 9, pp. 1192-201, (2012) (PubMed).
: "Functional dissection of lysine deacetylases reveals that HDAC1 and p300 regulate AMPK." in: Nature, Vol. 482, Issue 7384, pp. 251-5, (2012) (PubMed).
: "The energy sensor AMP-activated protein kinase directly regulates the mammalian FOXO3 transcription factor." in: The Journal of biological chemistry, Vol. 282, Issue 41, pp. 30107-19, (2007) (PubMed).
: "AMP-kinase regulates food intake by responding to hormonal and nutrient signals in the hypothalamus." in: Nature, Vol. 428, Issue 6982, pp. 569-74, (2004) (PubMed).
: "An activating mutation in the gamma1 subunit of the AMP-activated protein kinase." in: FEBS letters, Vol. 500, Issue 3, pp. 163-8, (2001) (PubMed).
Synonyms and alternative names related to PRKAG1
protein kinase, AMP-activated, gamma 1 non-catalytic subunit S homeolog (prkag1.S), protein kinase, AMP-activated, gamma 1 non-catalytic subunit (prkag1), protein kinase AMP-activated non-catalytic subunit gamma 1 (PRKAG1), protein kinase AMP-activated non-catalytic subunit gamma 1 (Prkag1), protein kinase, AMP-activated, gamma 1 non-catalytic subunit (Prkag1), AA571379, AMPKG, BB036179, MGC68503, Prkaac, Prkga1, wu:fa94d09, wu:fd12h04, zgc:63896Protein level used designations for PRKAG1
- protein kinase, AMP-activated, gamma 1 non-catalytic subunit
- 5'-AMP-activated protein kinase subunit gamma-1
- AMPK-activated protein kinase gamma-1 subunit
- AMP-activated protein kinase, noncatalytic gamma-1 subunit
- 5'-AMP-activated protein kinase subunit gamma-1-like
- 5'-AMP-activated protein kinase, gamma-1 subunit
- AMPK gamma-1 chain
- AMPK gamma1
- AMPK subunit gamma-1
- AMPKg
- Protein kinase AMP-activated gamma
- 38 kDa subunit
- 5'-AMP-activated protein kinase gamma-1 subunit
- AMP-activated protein kinase subunit gamma 1 (non-catalytic subunit)
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