蛋白简介

HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. The protein encoded by this gene is a transcriptional repressor that binds to chromosomally integrated TAR DNA and represses HIV-1 transcription. In addition, this protein regulates alternate splicing of the CFTR gene. A similar pseudogene is present on chromosome 20.

Alternative names and synonyms associated with TAR DNA Binding Protein (TARDBP)

• TAR DNA binding protein (TARDBP) 抗体
• Tardbp protein (tardbp) 抗体
• TAR DNA binding protein L homeolog (tardbp.L) 抗体
• TAR DNA binding protein (Tardbp) 抗体
• TAR DNA binding protein (tardbp) 抗体
• 显示所有的基因名称
• TAR DNA-binding protein 43-like (LOC100621383) 抗体

• 1190002A23Rik 抗体
• ALS10 抗体
• C85084 抗体
• DKFZp459I2127 抗体
• tardbp 抗体
• 显示所有的同义词和别名
• TDP-43 抗体
• Tdp43 抗体
• wu:fb77f02 抗体
• wu:fc52g10 抗体

Protein level used designations for TARDBP

TAR DNA binding protein , TAR DNA-binding protein 43 , Tardbp protein , TDP-43 , TAR DNA-binding protein-43