TNFSF15 抗体
(Tumor Necrosis Factor (Ligand) Superfamily, Member 15 (TNFSF15))
The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein is abundantly expressed in endothelial cells, but is not expressed in either B or T cells. The expression of this protein is inducible by TNF and IL-1 alpha. This cytokine is a ligand for receptor TNFRSF25 and decoy receptor TNFRSF21/DR6. It can activate NF-kappaB and MAP kinases, and acts as an autocrine factor to induce apoptosis in endothelial cells. This cytokine is also found to inhibit endothelial cell proliferation, and thus may function as an angiogenesis inhibitor. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2011].
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Latest Publications for our TNFSF15 抗体
: "TL1A as a potential local inducer of IL17A Expression in colon mucosa of inflammatory bowel disease patients." in: Scandinavian journal of immunology, (2015) (PubMed).: "TL1A-induced NF-kappaB activation and c-IAP2 production prevent DR3-mediated apoptosis in TF-1 cells." in: The Journal of biological chemistry, Vol. 278, Issue 40, pp. 39251-8, (2003) (PubMed).
: "Expression, localization, and functional activity of TL1A, a novel Th1-polarizing cytokine in inflammatory bowel disease." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 171, Issue 9, pp. 4868-74, (2003) (PubMed).
: "TRAMP, a novel apoptosis-mediating receptor with sequence homology to tumor necrosis factor receptor 1 and Fas(Apo-1/CD95)." in: Immunity, Vol. 6, Issue 1, pp. 79-88, (1997) (PubMed).
: "LARD: a new lymphoid-specific death domain containing receptor regulated by alternative pre-mRNA splicing." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 94, Issue 9, pp. 4615-9, (1997) (PubMed).
Aliases for TNFSF15 抗体
tumor necrosis factor superfamily member 15 (TNFSF15) 抗体TNF superfamily member 15 (TNFSF15) 抗体
tumor necrosis factor (ligand) superfamily, member 15 (Tnfsf15) 抗体
TNF superfamily member 15 (Tnfsf15) 抗体
TL1 抗体
Tl1 抗体
TL1A 抗体
Tl1a 抗体
TTPAL 抗体
VEGI 抗体
Vegi 抗体
VEGI192A 抗体
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