POT1 抗体
(Protection of Telomeres 1 (POT1))
This gene is a member of the telombin family and encodes a nuclear protein involved in telomere maintenance. Specifically, this protein functions as a member of a multi-protein complex that binds to the TTAGGG repeats of telomeres, regulating telomere length and protecting chromosome ends from illegitimate recombination, catastrophic chromosome instability, and abnormal chromosome segregation. Increased transcriptional expression of this gene is associated with stomach carcinogenesis and its progression. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2008].
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Latest Publications for our POT1 抗体
: "Telomere protein RAP1 levels are affected by cellular aging and oxidative stress." in: Biomedical reports, Vol. 5, Issue 2, pp. 181-187, (2016) (PubMed).: "Telomeres and Telomerase in the Radiation Response: Implications for Instability, Reprograming, and Carcinogenesis." in: Frontiers in oncology, Vol. 5, pp. 257, (2015) (PubMed).
: "Mir-23a induces telomere dysfunction and cellular senescence by inhibiting TRF2 expression." in: Aging cell, Vol. 14, Issue 3, pp. 391-9, (2015) (PubMed).
: "Bortezomib-mediated down-regulation of telomerase and disruption of telomere homeostasis contributes to apoptosis of malignant cells." in: Oncotarget, Vol. 6, Issue 35, pp. 38079-92, (2015) (PubMed).
: "T-oligo as an anticancer agent in colorectal cancer." in: Biochemical and biophysical research communications, Vol. 446, Issue 2, pp. 596-601, (2014) (PubMed).
: "Eroded human telomeres are more prone to remain uncapped and to trigger a G2 checkpoint response." in: Nucleic acids research, Vol. 41, Issue 2, pp. 900-11, (2013) (PubMed).
: "Telomere dysfunction and activation of alternative lengthening of telomeres in B-lymphocytes infected by Epstein-Barr virus." in: Oncogene, Vol. 32, Issue 49, pp. 5522-30, (2013) (PubMed).
: "The Epstein-Barr virus nuclear antigen-1 promotes telomere dysfunction via induction of oxidative stress." in: Leukemia, Vol. 25, Issue 6, pp. 1017-25, (2011) (PubMed).
: "Characterization of the DNA binding specificity of Shelterin complexes." in: Nucleic acids research, Vol. 39, Issue 21, pp. 9206-23, (2011) (PubMed).
: "Mechanism and substrate specificity of telomeric protein POT1 stimulation of the Werner syndrome helicase." in: Nucleic acids research, Vol. 36, Issue 13, pp. 4242-56, (2008) (PubMed).
Aliases for POT1 抗体
protection of telomeres 1 (POT1) 抗体protection of telomeres 1 L homeolog (pot1.L) 抗体
protection of telomeres 1A (Pot1a) 抗体
protection of telomeres 1 (Pot1) 抗体
1500031H18Rik 抗体
AI851169 抗体
DKFZp469P1825 抗体
HPOT1 抗体
POT1 抗体
pot1 抗体
Pot1 抗体
Pot1a 抗体
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