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POT1 抗体 (AA 247-296)

The 兔 多克隆 anti-POT1 antibody (ABIN1453800) specifically detects POT1 in WB 和 IHC. The antibody is reactive with 人 和 猴 samples.
产品编号 ABIN1453800
发货至: 中国
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Quick Overview for POT1 抗体 (AA 247-296) (ABIN1453800)

抗原

See all POT1 抗体
POT1 (Protection of Telomeres 1 (POT1))

适用

  • 56
  • 29
  • 28
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
人, 猴

宿主

  • 53
  • 3
兔

克隆类型

  • 53
  • 3
多克隆

标记

  • 26
  • 4
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This POT1 antibody is un-conjugated

应用范围

  • 28
  • 21
  • 14
  • 12
  • 4
  • 4
  • 2
Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

    • 13
    • 13
    • 5
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 247-296

    原理

    POT1 Antibody

    特异性

    POT1 Polyclonal Antibody detects endogenous levels of POT1 protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    免疫原

    The antiserum was produced against synthesized peptide derived from human POT1. AA range:247-296

    亚型

    IgG
  • 应用备注

    WB 1:500-2000,IHC 1:50-300

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    POT1 (Protection of Telomeres 1 (POT1))

    别名

    POT1

    背景

    Synonyms: POT1, Protection of telomeres protein 1, hPot1, POT1-like telomere end-binding protein

    Background: protection of telomeres 1(POT1) Homo sapiens This gene is a member of the telombin family and encodes a nuclear protein involved in telomere maintenance. Specifically, this protein functions as a member of a multi-protein complex that binds to the TTAGGG repeats of telomeres, regulating telomere length and protecting chromosome ends from illegitimate recombination, catastrophic chromosome instability, and abnormal chromosome segregation. Increased transcriptional expression of this gene is associated with stomach carcinogenesis and its progression. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2008],

    Gene Name: POT1

    Protein Name: Protection of telomeres protein 1

    分子量

    71 kDa

    基因ID

    25913

    OMIM

    606478

    UniProt

    Q9NUX5

    途径

    Cell Division Cycle, Telomere Maintenance
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