POT1 抗体 (AA 247-296)
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北京 101111
Quick Overview for POT1 抗体 (AA 247-296) (ABIN1453800)
抗原
See all POT1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 247-296
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原理
- POT1 Antibody
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特异性
- POT1 Polyclonal Antibody detects endogenous levels of POT1 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- The antiserum was produced against synthesized peptide derived from human POT1. AA range:247-296
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亚型
- IgG
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应用备注
- WB 1:500-2000,IHC 1:50-300
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- POT1 (Protection of Telomeres 1 (POT1))
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别名
- POT1
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背景
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Synonyms: POT1, Protection of telomeres protein 1, hPot1, POT1-like telomere end-binding protein
Background: protection of telomeres 1(POT1) Homo sapiens This gene is a member of the telombin family and encodes a nuclear protein involved in telomere maintenance. Specifically, this protein functions as a member of a multi-protein complex that binds to the TTAGGG repeats of telomeres, regulating telomere length and protecting chromosome ends from illegitimate recombination, catastrophic chromosome instability, and abnormal chromosome segregation. Increased transcriptional expression of this gene is associated with stomach carcinogenesis and its progression. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2008],
Gene Name: POT1
Protein Name: Protection of telomeres protein 1
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分子量
- 71 kDa
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基因ID
- 25913
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OMIM
- 606478
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UniProt
- Q9NUX5
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途径
- Cell Division Cycle, Telomere Maintenance
抗原
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