POLD4 抗体
(Polymerase (DNA-Directed), delta 4, Accessory Subunit (POLD4))
This gene encodes the smallest subunit of DNA polymerase delta. DNA polymerase delta possesses both polymerase and 3' to 5' exonuclease activity and plays a critical role in DNA replication and repair. The encoded protein enhances the activity of DNA polymerase delta and plays a role in fork repair and stabilization through interactions with the DNA helicase Bloom syndrome protein. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Mar 2012].
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Latest Publications for our POLD4 抗体
: "Roles of POLD4, smallest subunit of DNA polymerase delta, in nuclear structures and genomic stability of human cells." in: Biochemical and biophysical research communications, Vol. 391, Issue 1, pp. 542-6, (2010) (PubMed).: "Regulation of DNA polymerase POLD4 influences genomic instability in lung cancer." in: Cancer research, Vol. 70, Issue 21, pp. 8407-16, (2010) (PubMed).
: "A novel DNA damage response: rapid degradation of the p12 subunit of dna polymerase delta." in: The Journal of biological chemistry, Vol. 282, Issue 21, pp. 15330-40, (2007) (PubMed).
Aliases for POLD4 抗体
DNA polymerase delta 4, accessory subunit (POLD4) 抗体polymerase (DNA-directed), delta 4 (Pold4) 抗体
2410012M21Rik 抗体
AI463381 抗体
AW060307 抗体
p12 抗体
Polds 抗体
POLDS 抗体
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