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POLD4 产品

(Polymerase (DNA-Directed), delta 4, Accessory Subunit (POLD4))
This gene encodes the smallest subunit of DNA polymerase delta. DNA polymerase delta possesses both polymerase and 3' to 5' exonuclease activity and plays a critical role in DNA replication and repair. The encoded protein enhances the activity of DNA polymerase delta and plays a role in fork repair and stabilization through interactions with the DNA helicase Bloom syndrome protein. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Mar 2012].

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Featured POLD4 Categories

POLD4 抗体

High quality antibodies with extensive validation data.

POLD4 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended POLD4 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (3)
  • (2)
Cat. No. ABIN528317
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (2)
Cat. No. ABIN528318
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC
Validations
  • (2)
Cat. No. ABIN6264334
Quantity 100 μL
Datasheet Datasheet

Recommended POLD4 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7124519
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1315630
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
  • (1)
Cat. No. ABIN3078977
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our POLD4 Products

Huang, Akashi, Masuda, Kamiya, Takahashi, Suzuki: "Roles of POLD4, smallest subunit of DNA polymerase delta, in nuclear structures and genomic stability of human cells." in: Biochemical and biophysical research communications, Vol. 391, Issue 1, pp. 542-6, (2010) (PubMed).

Huang, Tomida, Masuda, Arima, Cao, Kasahara, Osada, Yatabe, Akashi, Kamiya, Takahashi, Suzuki: "Regulation of DNA polymerase POLD4 influences genomic instability in lung cancer." in: Cancer research, Vol. 70, Issue 21, pp. 8407-16, (2010) (PubMed).

Zhang, Zhou, Trusa, Meng, Lee, Lee: "A novel DNA damage response: rapid degradation of the p12 subunit of dna polymerase delta." in: The Journal of biological chemistry, Vol. 282, Issue 21, pp. 15330-40, (2007) (PubMed).

Synonyms and alternative names related to POLD4

DNA polymerase delta 4, accessory subunit (POLD4), polymerase (DNA-directed), delta 4 (Pold4), 2410012M21Rik, AI463381, AW060307, p12, Polds, POLDS

Protein level used designations for POLD4

  • DNA polymerase delta subunit 4
  • DNA polymerase delta subunit p12
  • DNA-directed DNA polymerase delta 4
  • DNA polymerase delta smallest subunit p12
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