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POFUT1 产品

(Protein O-Fucosyltransferase 1 (POFUT1))

Categories

This gene encodes a member of the glycosyltransferase O-Fuc family. This enzyme adds O-fucose through an O-glycosidic linkage to conserved serine or threonine residues in the epidermal growth factor-like repeats of a number of cell surface and secreted proteins. O-fucose glycans are involved in ligand-induced receptor signaling. Alternative splicing of this gene results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008].

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Featured POFUT1 Categories

POFUT1 抗体

High quality antibodies with extensive validation data.

POFUT1 ELISA试剂盒

Reliable ELISA kits for a wide range of species.

POFUT1 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended POFUT1 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (5)
Cat. No. ABIN7444553
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
  • (3)
Cat. No. ABIN525219
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Application WB, IHC, IP, ICC
Validations
  • (2)
Cat. No. ABIN7444556
Quantity 100 μL
Datasheet Datasheet

Recommended POFUT1 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6969730
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method
Validations
Cat. No. ABIN1134574
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method
Validations
Cat. No. ABIN1134573
Quantity 96 tests
Datasheet Datasheet

Recommended POFUT1 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1315608
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1315606
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3094357
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our POFUT1 Products

Wu, Xiong, Li, Yang, Ge et al.: "Integrated Proteomic and Transcriptomic Analysis Reveals Long Noncoding RNA HOX Transcript Antisense Intergenic RNA (HOTAIR) Promotes Hepatocellular Carcinoma Cell Proliferation by Regulating Opioid ..." in: Molecular & cellular proteomics : MCP, Vol. 17, Issue 1, pp. 146-159, (2019) (PubMed).

Takeuchi, Wong, Schneider, Freeze, Takeuchi, Berardinelli, Ito, Lee, Nelson, Haltiwanger: "Variant in human POFUT1 reduces enzymatic activity and likely causes a recessive microcephaly, global developmental delay with cardiac and vascular features." in: Glycobiology, Vol. 28, Issue 5, pp. 276-283, (2018) (PubMed).

Annani-Akollor, Wang, Fan, Liu, Padhiar, Zhang: "Downregulated protein O-fucosyl transferase 1 (Pofut1) expression exerts antiproliferative and antiadhesive effects on hepatocytes by inhibiting Notch signalling." in: Biomedicine & pharmacotherapy, Vol. 68, Issue 6, pp. 785-90, (2014) (PubMed).

Stahl, Uemura, Ge, Shi, Tashima, Stanley: "Roles of Pofut1 and O-fucose in mammalian Notch signaling." in: The Journal of biological chemistry, Vol. 283, Issue 20, pp. 13638-51, (2008) (PubMed).

Loriol, Dupuy, Rampal, Dlugosz, Haltiwanger, Maftah, Germot: "Molecular evolution of protein O-fucosyltransferase genes and splice variants." in: Glycobiology, Vol. 16, Issue 8, pp. 736-47, (2006) (PubMed).

Shi, Stanley: "Protein O-fucosyltransferase 1 is an essential component of Notch signaling pathways." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 100, Issue 9, pp. 5234-9, (2003) (PubMed).

Wang, Shao, Shi, Harris, Spellman, Stanley, Haltiwanger: "Modification of epidermal growth factor-like repeats with O-fucose. Molecular cloning and expression of a novel GDP-fucose protein O-fucosyltransferase." in: The Journal of biological chemistry, Vol. 276, Issue 43, pp. 40338-45, (2001) (PubMed).

Synonyms and alternative names related to POFUT1

protein O-fucosyltransferase 1 (POFUT1), protein O-fucosyltransferase 1 (pofut1), protein O-fucosyltransferase 1 (Pofut1), DDD2, fut12, FUT12, Fut12, mKIAA0180, o-fuc-t, O-Fuc-T, o-fuct-1, O-FucT-1, o-fut, O-FUT, OFUCT1, pofut1, zgc:110472

Protein level used designations for POFUT1

  • GDP-fucose protein O-fucosyltransferase 1
  • putative protein-O-fucosyltransferase
  • O-FucT-1
  • peptide-O-fucosyltransferase 1
  • protein-O-fucosyltransferase 1
  • protein-O-fucosyltransferase
  • protein O-fucosyltransferase 1
  • o-fucosyltransferase protein
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